Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4371737 | 0.94 | HSD11B1 (0.73) | HSD11B1CYP3A4 | |
| SCHEMBL13635942 | 0.85 | HSD11B1 (0.67) | HSD11B1CYP3A4 | |
| SCHEMBL14607213 | 0.84 | HSD11B1 (0.61) | HSD11B1CYP3A4 | |
| SCHEMBL4372522 | 0.84 | HSD11B1 (0.80) | HSD11B1CYP3A4 | |
| SCHEMBL4367323 | 0.83 | HSD11B1 (1.00) | HSD11B1CYP3A4 | |
| SCHEMBL4367417 | 0.83 | HSD11B1 (1.00) | HSD11B1CYP3A4 | |
| SCHEMBL4664254 | 0.81 | HSD11B1 (0.76) | HSD11B1CYP3A4 | |
| SCHEMBL4369155 | 0.81 | HSD11B1 (0.76) | HSD11B1CYP3A4 | |
| SCHEMBL4365106 | 0.80 | HSD11B1 (0.73) | HSD11B1CYP3A4 | |
| SCHEMBL15151458 | 0.79 | HSD11B1 (1.00) | HSD11B1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622492-B2 | Pyrazolones as inhibitors of 11β-hydroxysteroid dehydrogenase | HOFFMANN-LA ROCHE INC. (US) | 2009-11-24 | — | — | US | disclosed |