Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 3/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.31 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.31 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.31 |
| ▸ | PGK1 | P00558 | 1/20 | 0.31 |
| ▸ | PGK2 | P07205 | 1/20 | 0.31 |
| ▸ | ENPP2 | Q13822 | 4/20 | 0.31 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.31 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.30 |
| ▸ | LPAR4 | Q99677 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8407485 | 1.00 | SMPD1 (0.36) | SMPD1PIK3CDALDH1A1LPAR3LPAR1 | |
| SCHEMBL18372917 | 0.87 | LPAR5 (0.34) | SMPD1LPAR3LPAR1LPAR5 | |
| SCHEMBL21291928 | 0.86 | PIK3CD (0.32) | PIK3CD | |
| SCHEMBL1574058 | 0.81 | PGK1 (0.45) | LPAR3LPAR1LPAR2PGK1PGK2 | |
| SCHEMBL5432672 | 0.81 | SMPD1 (0.36) | SMPD1PGK1PGK2 | |
| SCHEMBL26188134 | 0.79 | TSHR (0.35) | SMPD1ALDH1A1LPAR3LPAR1LPAR5 | |
| SCHEMBL38660044 | 0.79 | MMP1 (0.34) | SMPD1LPAR3LPAR1LPAR2PGK1 | |
| SCHEMBL29143313 | 0.79 | TDP1 (0.50) | SMPD1LPAR3LPAR1LPAR2LPAR5 | |
| SCHEMBL38660842 | 0.79 | MMP1 (0.34) | SMPD1LPAR3LPAR1LPAR2PGK1 | |
| Phosphoric Acid SCHEMBL11590026 | 0.78 | MMP1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1314033-B1 | IMMOBILISED PHOSPHATIDIC ACID PROBE | HOLMES ANDREW BRUCE (GB) | 2009-11-18 | — | — | EP | disclosed |