Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC28A1 | O00337 | 1/20 | 0.56 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.56 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.56 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.56 |
| ▸ | PYGM | P11217 | 3/20 | 0.53 |
| ▸ | TK2 | O00142 | 2/20 | 0.46 |
| ▸ | CDK1 | P06493 | 1/20 | 0.45 |
| ▸ | CDA | P32320 | 2/20 | 0.44 |
| ▸ | PNP | P00491 | 1/20 | 0.44 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12143537 | 1.00 | SLC28A1 (0.56) | SLC28A1SLC28A2SLC29A1SLC28A3PYGM | |
| SCHEMBL15196241 | 1.00 | SLC28A1 (0.56) | SLC28A1SLC28A2SLC29A1SLC28A3PYGM | |
| SCHEMBL12143120 | 1.00 | SLC28A1 (0.56) | SLC28A1SLC28A2SLC29A1SLC28A3PYGM | |
| SCHEMBL14146696 | 1.00 | SLC28A1 (0.56) | SLC28A1SLC28A2SLC29A1SLC28A3PYGM | |
| SCHEMBL1363611 | 1.00 | SLC28A1 (0.56) | SLC28A1SLC28A2SLC29A1SLC28A3PYGM | |
| SCHEMBL15196264 | 1.00 | SLC28A1 (0.56) | SLC28A1SLC28A2SLC29A1SLC28A3PYGM | |
| SCHEMBL16871907 | 1.00 | SLC28A1 (0.56) | SLC28A1SLC28A2SLC29A1SLC28A3PYGM | |
| Phosphoric Acid SCHEMBL3488257 | 0.95 | SLC28A1 (0.52) | SLC28A1SLC28A2SLC29A1SLC28A3PYGM | |
| SCHEMBL4635274 | 0.86 | P2RY2 (0.47) | SLC28A1SLC28A2SLC29A1SLC28A3PYGM | |
| SCHEMBL8134028 | 0.85 | SLC28A1 (0.58) | SLC28A1SLC28A2SLC29A1SLC28A3PYGM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1931691-B1 | ODCASE INHIBITORS FOR THE TREATMENT OF MALARIA | UNIV HEALTH NETWORK (CA) | 2013-08-21 | — | — | EP | claimed |
| CN-101321775-B | ODCASE inhibitors for the treatment of malaria | UNIV HEALTH NETWORK | 2012-05-23 | — | — | CN | claimed |
| US-8067391-B2 | ODCase inhibitors for the treatment of malaria | UNIVERSITY HEALTH NETWORK (CA) | 2011-11-29 | — | — | US | claimed |
| US-20100056468-A1 | Pyrimidine Derivatives As Anticancer Agents | UNIVERSITY HEALTH NETWORK (CA) | 2010-03-04 | — | — | US | claimed |
| US-20090221524-A1 | ODCASE INHIBITORS FOR THE TREATMENT OF MALARIA | UNIVERSITY HEALTH NETWORK (CA) | 2009-09-03 | — | — | US | claimed |
| CN-101321775-A | ODCASE inhibitors for the treatment of malaria | UNIV HEALTH NETWORK (CA) | 2008-12-10 | — | — | CN | claimed |
| WO-2008083465-A1 | PYRIMIDINE DERIVATIVES AS ANTICANCER AGENTS | UNIVERSITY HEALTH NETWORK (CA) | 2008-07-17 | — | — | WO | claimed |
| EP-1931691-A1 | ODCASE INHIBITORS FOR THE TREATMENT OF MALARIA | University Health Network (CA) | 2008-06-18 | — | — | EP | claimed |
| WO-2007038859-A1 | ODCASE INHIBITORS FOR THE TREATMENT OF MALARIA | UNIVERSITY HEALTH NETWORK (CA) | 2007-04-12 | — | — | WO | claimed |
| US-6020483-A | Nucleoside modifications by palladium catalyzed methods | NEXSTAR PHARMACEUTICALS, INC. (US) | 2000-02-01 | — | — | US | claimed |
| CN-121678872-A | Method for detecting iodo-nucleoside in drinking water by solid phase extraction-vacuum centrifugal concentration-liquid chromatography tandem mass spectrometry | 浙江大学 | 2026-03-17 | — | — | CN | disclosed |
| US-11357774-B2 | Use of a quinoline sulfonyl compound for treatment of inflammation, inflammatory disorders, autoimmune disorders and malaria | LEE HOYUN (CA) | 2022-06-14 | — | — | US | disclosed |
| US-20200281920-A1 | USE OF A QUINOLINE SULFONYL COMPOUND FOR TREATMENT OF INFLAMMATION, INFLAMMATORY DISORDERS, AUTOIMMUNE DISORDERS AND MALARIA | LEE HOYUN (CA) | 2020-09-10 | — | — | US | disclosed |
| EP-1931691-B1 | ODCASE INHIBITORS FOR THE TREATMENT OF MALARIA | UNIV HEALTH NETWORK (CA) | 2013-08-21 | — | — | EP | disclosed |
| CN-101321775-B | ODCASE inhibitors for the treatment of malaria | UNIV HEALTH NETWORK | 2012-05-23 | — | — | CN | disclosed |
| WO-2007038860-A8 | ODCASE INHIBITORS AS ANTI-VIRALS AND ANTIBIOTICS | UNIV HEALTH NETWORK (CA) | 2007-12-21 | — | — | WO | disclosed |
| WO-2007038860-A3 | ODCASE INHIBITORS AS ANTI-VIRALS AND ANTIBIOTICS | KOTRA LAKSHMI P (CA) | 2007-06-07 | — | — | WO | disclosed |
| WO-2007038860-A2 | ODCASE INHIBITORS AS ANTI-VIRALS AND ANTIBIOTICS | UNIVERSITY HEALTH NETWORK (CA) | 2007-04-12 | — | — | WO | disclosed |
| WO-2007038860-A2 | ODCASE INHIBITORS AS ANTI-VIRALS AND ANTIBIOTICS | UNIVERSITY HEALTH NETWORK (CA) | 2007-04-12 | — | — | WO | disclosed |
| WO-2007038859-A1 | ODCASE INHIBITORS FOR THE TREATMENT OF MALARIA | UNIVERSITY HEALTH NETWORK (CA) | 2007-04-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090221524-A1 | ODCASE INHIBITORS FOR THE TREATMENT OF MALARIA | UMPS, UGDH, UPP1 | SLC28A1 415/4885SLC28A2 455/4885SLC29A1 271/4885 |
| US-20200281920-A1 | USE OF A QUINOLINE SULFONYL COMPOUND FOR TREATMENT OF INFLAMMATION, INFLAMMATORY DISORDERS, AUTOIMMUNE DISORDERS AND MALARIA | IL17A, IL23R, CASP1 | SLC28A1 487/4885SLC28A2 870/4885SLC29A1 1773/4885 |
| US-20100056468-A1 | Pyrimidine Derivatives As Anticancer Agents | DPYD, TYMP, TYMS | SLC28A1 165/4885SLC28A2 198/4885SLC29A1 58/4885 |
| US-11357774-B2 | Use of a quinoline sulfonyl compound for treatment of inflammation, inflammatory disorders, autoimmune disorders and malaria | IL17A, IL23R, CASP1 | SLC28A1 487/4885SLC28A2 870/4885SLC29A1 1773/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.