Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A1 | P43005 | 6/20 | 0.64 |
| ▸ | SLC1A3 | P43003 | 5/20 | 0.64 |
| ▸ | SLC1A2 | P43004 | 5/20 | 0.64 |
| ▸ | HTR2A | P28223 | 1/20 | 0.56 |
| ▸ | HTR2C | P28335 | 1/20 | 0.56 |
| ▸ | HTR2B | P41595 | 1/20 | 0.56 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.50 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 2/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.48 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.47 |
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.46 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.46 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.46 |
| ▸ | GRB2 | P62993 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29478401 | 0.87 | HTR2A (0.64) | HTR2AHTR2CHTR2BPPARAPPARG | |
| SCHEMBL503602 | 0.87 | HTR2A (0.64) | HTR2AHTR2CHTR2BPPARAPPARG | |
| SCHEMBL44155 | 0.87 | HTR2A (0.64) | HTR2AHTR2CHTR2BPPARAPPARG | |
| SCHEMBL44156 | 0.87 | HTR2A (0.64) | HTR2AHTR2CHTR2BPPARAPPARG | |
| SCHEMBL29557134 | 0.87 | HTR2A (0.64) | HTR2AHTR2CHTR2BPPARAPPARG | |
| Hydrochloric Acid SCHEMBL10584250 | 0.86 | HTR2A (0.62) | SLC1A1SLC1A3SLC1A2HTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL6775624 | 0.86 | HTR2A (0.62) | SLC1A1SLC1A3SLC1A2HTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL6775619 | 0.86 | HTR2A (0.62) | SLC1A1SLC1A3SLC1A2HTR2AHTR2C | |
| SCHEMBL1816528 | 0.85 | HTR2A (0.56) | HTR2AHTR2CHTR2BPPARAPPARG | |
| SCHEMBL12762359 | 0.83 | SLC1A3 (0.67) | SLC1A1SLC1A3SLC1A2GRIK1GRIK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009141079-A1 | NOVEL [F-18]-LABELLED L-GLUTAMIC ACID AND L-GLUTAMINE DERIVATIVES (II), USE THEREOF AND METHOD FOR THEIR PRODUCTION | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-11-26 | — | — | WO | disclosed |