SCHEMBL29478401

SCHEMBL29478401

N[C@H](Cc1cccc(C(F)(F)F)c1)C(=O)O

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 2/20 0.64
HTR2C P28335 1/20 0.64
HTR2B P41595 1/20 0.64
GRB2 P62993 1/20 0.59
SLC7A5 Q01650 7/20 0.59
PTGS1 P23219 2/20 0.59
ALPI P09923 1/20 0.59
PKM P14618 1/20 0.59
XIAP P98170 1/20 0.59
GRIA2 P42262 1/20 0.56
NOS3 P29474 2/20 0.55
NOS1 P29475 2/20 0.55
NOS2 P35228 2/20 0.55
PPARG P37231 1/20 0.55
PPARA Q07869 1/20 0.55
EPHX1 P07099 1/20 0.54
DPP4 P27487 1/20 0.53
DPP8 Q6V1X1 1/20 0.53
DPP9 Q86TI2 1/20 0.53
DPP7 Q9UHL4 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29557134 1.00 HTR2A (0.64) HTR2AHTR2CHTR2BGRB2SLC7A5
SCHEMBL503602 1.00 HTR2A (0.64) HTR2AHTR2CHTR2BGRB2SLC7A5
SCHEMBL44156 1.00 HTR2A (0.64) HTR2AHTR2CHTR2BGRB2SLC7A5
SCHEMBL44155 1.00 HTR2A (0.64) HTR2AHTR2CHTR2BGRB2SLC7A5
Hydrochloric Acid SCHEMBL10584250 0.98 HTR2A (0.62) HTR2AHTR2CHTR2BGRB2SLC7A5
Hydrochloric Acid SCHEMBL6775624 0.98 HTR2A (0.62) HTR2AHTR2CHTR2BGRB2SLC7A5
Hydrochloric Acid SCHEMBL6775619 0.98 HTR2A (0.62) HTR2AHTR2CHTR2BGRB2SLC7A5
SCHEMBL6831079 0.88 PPARG (0.60) HTR2AHTR2CHTR2BGRB2SLC7A5
SCHEMBL16131653 0.88 HTR2A (0.69) HTR2AHTR2CHTR2BEPHX1DPP4
SCHEMBL19943590 0.88 HTR2A (0.69) HTR2AHTR2CHTR2BEPHX1DPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025245483-A1 METHODS AND COMPOSITIONS FLAGSHIP PIONEERING INNOVATIONS VII, LLC (US) 2025-11-27 WO disclosed
US-20250361273-A1 METHODS AND COMPOSITIONS FLAGSHIP PIONEERING INNOVATIONS VII, LLC 2025-11-27 US disclosed
CN-120202010-A Ligand-oligonucleotide conjugates and linkers for use therewith 上海京新生物医药有限公司 2025-06-24 CN disclosed
EP-4504732-A2 NANOMATERIAL DELIVERY VEHICLE AND METHOD OF USE THEREOF University of Connecticut (US) 2025-02-12 EP disclosed
CN-118879592-A Unnatural base pair compositions and methods of use 斯克利普斯研究所 2024-11-01 CN disclosed
CN-112105627-B Unnatural base pair compositions and methods of use 斯克利普斯研究所 2024-07-02 CN disclosed
CN-118139868-A Orally bioavailable nucleoside analogs 维纳拓尔斯制药公司 2024-06-04 CN disclosed
EP-4355755-A1 ORALLY-BIOAVAILABLE NUCLEOSIDE ANALOGS Venatorx Pharmaceuticals, Inc. (US) 2024-04-24 EP disclosed
WO-2024043250-A1 CYCLIC PEPTIDE OR SALT THEREOF, AND MDMX INHIBITOR 富士フイルム株式会社 2024-02-29 WO disclosed
CN-111182880-B WNT compositions and process from serum-free culture conditions 安卡萨再生疗法公司 2024-01-09 CN disclosed
CN-114761026-A Compositions and methods for in vivo synthesis of non-native polypeptides 斯克利普斯研究所 2022-07-15 CN disclosed
CN-114746099-A Eukaryotic semisynthetic organisms 斯克利普斯研究所 2022-07-12 CN disclosed
CN-112500466-B Peptidomimetic macrocycles 艾瑞朗医疗公司 2022-05-03 CN disclosed
EP-3983543-A1 REAGENTS AND METHODS FOR REPLICATION, TRANSCRIPTION, AND TRANSLATION IN SEMI-SYNTHETIC ORGANISMS The Scripps Research Institute (US) 2022-04-20 EP disclosed
EP-3976635-A1 METHODS OF TREATING HYPERLIPIDEMIA CONDITIONS WITH NETRIN-1 COMPOUNDS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-04-06 EP disclosed
CN-114269367-A Therapeutic peptides 科巴公司 2022-04-01 CN disclosed
CN-108348571-B Peptidomimetic macrocycles and uses thereof 艾瑞朗医疗公司 2022-03-22 CN disclosed
CN-114206911-A Methods of treating hyperlipidemia disorders with axon-targeting factor-1 compounds 加利福尼亚大学董事会 2022-03-18 CN disclosed
CN-114207129-A Agents and methods for replication, transcription and translation in semi-synthetic organisms 斯克利普斯研究所 2022-03-18 CN disclosed
CN-114173878-A Peptidomimetic macrocycles and uses thereof 艾瑞朗医疗公司 2022-03-11 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250361273-A1 METHODS AND COMPOSITIONS MC4R, GPR119, MC2R HTR2A 219/4885HTR2C 265/4885HTR2B 373/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.