SCHEMBL503602

SCHEMBL503602

N[C@H](Cc1cccc(C(F)(F)F)c1)C(=O)O

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 2/20 0.64
HTR2C P28335 1/20 0.64
HTR2B P41595 1/20 0.64
GRB2 P62993 1/20 0.59
SLC7A5 Q01650 7/20 0.59
PTGS1 P23219 2/20 0.59
ALPI P09923 1/20 0.59
PKM P14618 1/20 0.59
XIAP P98170 1/20 0.59
GRIA2 P42262 1/20 0.56
NOS3 P29474 2/20 0.55
NOS1 P29475 2/20 0.55
NOS2 P35228 2/20 0.55
PPARG P37231 1/20 0.55
PPARA Q07869 1/20 0.55
EPHX1 P07099 1/20 0.54
DPP4 P27487 1/20 0.53
DPP8 Q6V1X1 1/20 0.53
DPP9 Q86TI2 1/20 0.53
DPP7 Q9UHL4 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29557134 1.00 HTR2A (0.64) HTR2AHTR2CHTR2BGRB2SLC7A5
SCHEMBL44156 1.00 HTR2A (0.64) HTR2AHTR2CHTR2BGRB2SLC7A5
SCHEMBL44155 1.00 HTR2A (0.64) HTR2AHTR2CHTR2BGRB2SLC7A5
SCHEMBL29478401 1.00 HTR2A (0.64) HTR2AHTR2CHTR2BGRB2SLC7A5
Hydrochloric Acid SCHEMBL10584250 0.98 HTR2A (0.62) HTR2AHTR2CHTR2BGRB2SLC7A5
Hydrochloric Acid SCHEMBL6775624 0.98 HTR2A (0.62) HTR2AHTR2CHTR2BGRB2SLC7A5
Hydrochloric Acid SCHEMBL6775619 0.98 HTR2A (0.62) HTR2AHTR2CHTR2BGRB2SLC7A5
SCHEMBL6831079 0.88 PPARG (0.60) HTR2AHTR2CHTR2BGRB2SLC7A5
SCHEMBL16131653 0.88 HTR2A (0.69) HTR2AHTR2CHTR2BEPHX1DPP4
SCHEMBL19943590 0.88 HTR2A (0.69) HTR2AHTR2CHTR2BEPHX1DPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 326 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260083834-A1 CsgA-DERIVED NANOSTRUCTURES AND USES THEREOF FOR ANTIGEN DELIVERY TRANSFERT PLUS LP (CA) 2026-03-26 US disclosed
US-20260001846-A1 SPIROCYCLOHEXANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS ANTI-APOPTOTIC INHIBITORS SERVIER LAB (FR) 2026-01-01 US disclosed
US-20260001924-A1 NEMO COILED COIL MIMICS AND METHODS OF USING SAME NEW YORK UNIVERSITY (US) 2026-01-01 US disclosed
US-20250367300-A1 Nanomaterial and Methods of Use Thereof UNIVERSITY OF CONNECTICUT (US) 2025-12-04 US disclosed
WO-2025245483-A1 METHODS AND COMPOSITIONS FLAGSHIP PIONEERING INNOVATIONS VII, LLC (US) 2025-11-27 WO disclosed
US-20250361273-A1 METHODS AND COMPOSITIONS FLAGSHIP PIONEERING INNOVATIONS VII, LLC 2025-11-27 US disclosed
US-20250302762-A1 NANOMATERIAL DELIVERY VEHICLE AND METHOD OF USE THEREOF UNIVERSITY OF CONNECTICUT (US) 2025-10-02 US disclosed
US-20250302971-A1 Therapeutic Nanomaterials UNIV CONNECTICUT (US) 2025-10-02 US disclosed
US-12371461-B2 Nemo coiled coil mimics and methods of using same NEW YORK UNIVERSITY (US) 2025-07-29 US disclosed
US-20250229081-A1 NANOMATERIAL COATED ELECTRODE AND METHODS OF USE THEREOF UNIVERSITY OF CONNECTICUT 2025-07-17 US disclosed
US-20050124548-A1 Peptide antiangiogenic drugs HENKIN JACK (US) 2005-06-09 US disclosed
US-6774211-B1 Peptide antiangiogenic drugs ABBOTT LABORATORIES 2004-08-10 US disclosed
US-6716963-B1 OLIGOPEPTIDES ABBOTT LABORATORIES 2004-04-06 US disclosed
US-20030148936-A1 Bioactive peptides ALPHARMA AS. 2003-08-07 US disclosed
EP-1263471-A2 ANTIMICROBIAL COMPOUNDS AND FORMULATIONS ALPHARMA AS (NO) 2002-12-11 EP disclosed
WO-2001066147-A2 ANTIMICROBIAL COMPOUNDS AND FORMULATIONS ALPHARMA AS (NO) 2001-09-13 WO disclosed
EP-1109831-A2 CYCTOTOXIC PEPTIDES MODIFIED BY BULKY OR LIPOPHILIC MOIETIES ALPHARMA AS (NO) 2001-06-27 EP disclosed
EP-1109827-A2 BIOACTIVE PEPTIDES ALPHARMA AS (NO) 2001-06-27 EP disclosed
WO-2000012542-A2 CYTOTOXIC LACTOFERRIN DERIVATIVES MODIFIED BY BULKY OR LIPOPHILIC MOIETIES ALPHARMA AS (NO) 2000-03-09 WO disclosed
WO-2000012541-A2 CYTOTOXIC PEPTIDES MODIFIED BY BULKY OR LIPOPHILIC MOIETIES ALPHARMA AS (NO) 2000-03-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250302971-A1 Therapeutic Nanomaterials TIE1, TEKT1, POLRMT HTR2A 4346/4885HTR2C 4711/4885HTR2B 4355/4885
US-20250367300-A1 Nanomaterial and Methods of Use Thereof EPCAM, CD47, JAK2 HTR2A 4741/4885HTR2C 4698/4885HTR2B 4285/4885
US-12371461-B2 Nemo coiled coil mimics and methods of using same COIL, CALCOCO2, NCAPH HTR2A 2891/4885HTR2C 2681/4885HTR2B 3072/4885
US-20250302762-A1 NANOMATERIAL DELIVERY VEHICLE AND METHOD OF USE THEREOF JAK2, JAK1, CHMP4B HTR2A 4511/4885HTR2C 4432/4885HTR2B 4360/4885
US-20260001846-A1 SPIROCYCLOHEXANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS ANTI-APOPTOTIC INHIBITORS BCL2, BCL2A1, BAX HTR2A 3518/4885HTR2C 3285/4885HTR2B 3413/4885
US-20050124548-A1 Peptide antiangiogenic drugs VEGFA, NPPA, FLT1 HTR2A 1318/4885HTR2C 4190/4885HTR2B 1289/4885
US-20030148936-A1 Bioactive peptides VIP, NGLY1, HM13 HTR2A 4824/4885HTR2C 4873/4885HTR2B 4421/4885
US-20260083834-A1 CsgA-DERIVED NANOSTRUCTURES AND USES THEREOF FOR ANTIGEN DELIVERY VSIG8, MICA, CD74 HTR2A 4794/4885HTR2C 4856/4885HTR2B 4849/4885
US-20250361273-A1 METHODS AND COMPOSITIONS MC4R, GPR119, MC2R HTR2A 219/4885HTR2C 265/4885HTR2B 373/4885
US-20260001924-A1 NEMO COILED COIL MIMICS AND METHODS OF USING SAME DDX21, PHAX, RBX1 HTR2A 2915/4885HTR2C 3112/4885HTR2B 3320/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.