Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CCR5 | P51681 | 1/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.45 |
| ▸ | TACR1 | P25103 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13090092 | 0.90 | L3MBTL3 (0.64) | ALDH1A1KMT2ATSHRL3MBTL3POLB | |
| SCHEMBL9345400 | 0.83 | NPC1 (0.61) | ALDH1A1KMT2APOLBMAPT | |
| SCHEMBL9350110 | 0.82 | NPC1 (0.59) | ALDH1A1KMT2APOLBMAPT | |
| SCHEMBL4377238 | 0.81 | KMT2A (0.71) | ALDH1A1KMT2ATSHRL3MBTL3KDM4E | |
| SCHEMBL4378534 | 0.81 | KMT2A (0.62) | ALDH1A1KMT2ATSHRL3MBTL3KDM4E | |
| SCHEMBL4375187 | 0.80 | KMT2A (0.73) | ALDH1A1KMT2ATSHRL3MBTL3 | |
| SCHEMBL4379319 | 0.80 | KMT2A (0.64) | ALDH1A1KMT2ATSHRL3MBTL3KDM4E | |
| SCHEMBL9346536 | 0.80 | IAPP (0.53) | KMT2ATSHRMAPTROCK2 | |
| SCHEMBL13636198 | 0.79 | ALDH1A1 (0.56) | ALDH1A1KMT2ATSHRL3MBTL3KDM4E | |
| SCHEMBL4383272 | 0.79 | ALDH1A1 (0.98) | ALDH1A1KMT2ATSHRL3MBTL3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1421071-B1 | SUBSTITUTED PIPERAZINE AND DIAZEPANE DERIVAIVES AS HISTAMINE H3 RECEPTOR MODULATORS | HIGH POINT PHARMACEUTICALS LLC (US) | 2009-11-18 | — | — | EP | disclosed |