Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.34 |
| ▸ | CPS1 | P31327 | 2/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19449734 | 0.84 | CPS1 (0.36) | ESR1ESR2MGLLMEN1KMT2A | |
| SCHEMBL24445679 | 0.82 | CES2 (0.52) | ESR1ESR2MGLLMEN1KMT2A | |
| SCHEMBL21882640 | 0.79 | MAPT (0.40) | MEN1KMT2ALOXL2KDM4EMAPT | |
| SCHEMBL17133958 | 0.79 | MEN1 (0.43) | ESR1ESR2MGLLMEN1KMT2A | |
| SCHEMBL15761201 | 0.79 | MEN1 (0.43) | ESR1ESR2MGLLMEN1KMT2A | |
| SCHEMBL8903721 | 0.79 | KMT2A (0.47) | ESR1ESR2MGLLMEN1KMT2A | |
| SCHEMBL10147452 | 0.79 | KMT2A (0.47) | ESR1ESR2MGLLMEN1KMT2A | |
| SCHEMBL18502966 | 0.78 | MEN1 (0.35) | ESR1ESR2MGLLMEN1KMT2A | |
| SCHEMBL17730395 | 0.78 | GAA (0.42) | KMT2ALOXL2CSNK2A1MAPT | |
| SCHEMBL17737798 | 0.78 | GAA (0.42) | KMT2ALOXL2CSNK2A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760811-B1 | IMIDAZOLE DERIVATIVES AS HISTAMINE RECEPTOR H3 MODULATORS | INST NAT SANTE RECH MED (FR) | 2009-11-18 | — | — | EP | disclosed |