Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 1/20 | 0.36 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27437254 | 0.81 | CYP1A2 (0.50) | METAP1METAP2CYP1A2 | |
| SCHEMBL11982905 | 0.78 | — | — | |
| SCHEMBL1678740 | 0.78 | — | — | |
| SCHEMBL23050301 | 0.76 | CYP1A2 (0.41) | METAP1METAP2CYP1A2 | |
| SCHEMBL20003525 | 0.73 | METAP1 (0.48) | METAP1METAP2CYP1A2 | |
| SCHEMBL12262722 | 0.73 | METAP1 (0.48) | METAP1METAP2CYP1A2 | |
| SCHEMBL23312962 | 0.73 | METAP1 (0.33) | METAP1METAP2CYP1A2 | |
| SCHEMBL24466581 | 0.72 | METAP1 (0.37) | METAP1METAP2 | |
| SCHEMBL22229853 | 0.71 | METAP1 (0.52) | METAP1METAP2CYP1A2 | |
| SCHEMBL2062321 | 0.71 | METAP1 (0.52) | METAP1METAP2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242385-B1 | CYTOKINE, ESPECIALLY TNF-ALPHA, INHIBITORS | PHARMACOPEIA INC (US) | 2009-11-25 | — | — | EP | disclosed |