Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 1/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19752589 | 0.79 | SHBG (0.45) | — | |
| SCHEMBL1443658 | 0.77 | SHBG (0.46) | METAP1METAP2CYP1A2 | |
| SCHEMBL4745176 | 0.75 | SHBG (0.33) | CYP1A2 | |
| SCHEMBL13636616 | 0.73 | METAP1 (0.36) | METAP1METAP2CYP1A2 | |
| SCHEMBL19988266 | 0.72 | — | — | |
| SCHEMBL3406430 | 0.69 | CYP1A2 (0.43) | METAP1METAP2CYP1A2 | |
| SCHEMBL2989483 | 0.69 | CYP1A2 (0.43) | METAP1METAP2CYP1A2 | |
| SCHEMBL3367032 | 0.69 | CYP1A2 (0.43) | METAP1METAP2CYP1A2 | |
| SCHEMBL1678740 | 0.69 | — | — | |
| SCHEMBL20219186 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3812462-A1 | MODIFIED DOUBLE-STRANDED RNA AGENTS | Alnylam Pharmaceuticals, Inc. (US) | 2021-04-28 | — | — | EP | disclosed |