Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | PTGES | O14684 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
| ▸ | GCGR | P47871 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19999359 | 0.86 | CYP11B1 (0.34) | CYP11B1CYP11B2PTGS2RPS6KA3CYP1A2 | |
| SCHEMBL17942997 | 0.82 | ACHE (0.42) | CYP11B1CYP11B2PTGS2RPS6KA3KDM4E | |
| SCHEMBL18121304 | 0.82 | CYP11B1 (0.43) | CYP11B1CYP11B2MAPTKDM4EMEN1 | |
| SCHEMBL16258066 | 0.79 | KDM4E (0.40) | CYP11B1CYP11B2PTGS2RPS6KA3KDM4E | |
| SCHEMBL14365638 | 0.79 | ACHE (0.39) | CYP11B1CYP11B2PTGS2RPS6KA3KDM4E | |
| SCHEMBL16258104 | 0.79 | KDM4E (0.40) | CYP11B1CYP11B2PTGS2RPS6KA3KDM4E | |
| SCHEMBL16258100 | 0.77 | NFE2L2 (0.47) | CYP11B1CYP11B2PTGS2RPS6KA3KDM4E | |
| SCHEMBL14002519 | 0.77 | NFE2L2 (0.47) | CYP11B1CYP11B2PTGS2RPS6KA3KDM4E | |
| SCHEMBL12696827 | 0.77 | ACHE (0.54) | RPS6KA3MAPTKDM4EMEN1KMT2A | |
| SCHEMBL13636536 | 0.76 | AKR1C3 (0.35) | PTGS2RPS6KA3DHODHPDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2123623-A1 | LIQUID CRYSTALLINE COMPOUND, LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL DISPLAY ELEMENT | Chisso Corporation (JP) | 2009-11-25 | — | — | EP | disclosed |