Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 9/20 | 0.76 |
| ▸ | HTR2A | P28223 | 4/20 | 0.55 |
| ▸ | HTR2C | P28335 | 4/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13790315 | 0.89 | NFE2L2 (0.96) | NFE2L2HTR2AHTR2CKCNH2PTGS1 | |
| SCHEMBL21030098 | 0.87 | NFE2L2 (1.00) | NFE2L2HTR2AHTR2CKCNH2PTGS1 | |
| SCHEMBL29403420 | 0.86 | NFE2L2 (0.71) | NFE2L2HTR2AHTR2CKCNH2PTGS1 | |
| SCHEMBL11895622 | 0.86 | NFE2L2 (0.71) | NFE2L2HTR2AHTR2CKCNH2PTGS1 | |
| SCHEMBL11895621 | 0.86 | NFE2L2 (0.71) | NFE2L2HTR2AHTR2CKCNH2PTGS1 | |
| SCHEMBL14526427 | 0.81 | NFE2L2 (0.66) | NFE2L2HTR2AHTR2CKCNH2PTGS1 | |
| SCHEMBL13636755 | 0.80 | APP (0.68) | NFE2L2PTGS1PTGS2APP | |
| SCHEMBL13636778 | 0.80 | NFE2L2 (0.49) | NFE2L2HTR2AHTR2CKCNH2PTGS1 | |
| SCHEMBL20995877 | 0.80 | NFE2L2 (1.00) | NFE2L2HTR2AHTR2CKCNH2PTGS1 | |
| SCHEMBL20995870 | 0.80 | NFE2L2 (1.00) | NFE2L2HTR2AHTR2CKCNH2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1957605-B1 | ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2017-01-11 | — | — | EP | disclosed |
| US-8304095-B2 | Organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2012-11-06 | — | — | US | disclosed |
| US-8304095-B2 | Organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2012-11-06 | — | — | US | disclosed |
| US-20080272693-A1 | Organic Electroluminescent Devices | MERCK PATENT GMBH (DE) | 2008-11-06 | — | — | US | disclosed |
| US-20080272693-A1 | Organic Electroluminescent Devices | MERCK PATENT GMBH (DE) | 2008-11-06 | — | — | US | disclosed |
| WO-2007065549-A1 | ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2007-06-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080272693-A1 | Organic Electroluminescent Devices | EML4, MT-ND4L, EPCAM | NFE2L2 423/4885HTR2A 3106/4885HTR2C 3772/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.