Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | TNF | P01375 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3494879 | 0.84 | HSD11B1 (0.46) | HSD11B1ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL3493018 | 0.84 | HSD11B1 (0.46) | HSD11B1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL4773217 | 0.82 | PTGDR2 (0.55) | HSD11B1ALDH1A1MAPTKDM4ECYP2C19 | |
| SCHEMBL3492576 | 0.82 | KMT2A (0.46) | HSD11B1ALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL3491420 | 0.81 | HSD11B1 (0.50) | HSD11B1ALDH1A1MAPTKDM4EKMT2A | |
| SCHEMBL3493327 | 0.79 | HSD11B1 (0.45) | HSD11B1PTGS2PTGDR2 | |
| SCHEMBL14270838 | 0.77 | HSD11B1 (0.45) | HSD11B1ALDH1A1KDM4ECYP3A4USP2 | |
| SCHEMBL7498254 | 0.77 | PTGDR2 (0.49) | HSD11B1ALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL4705593 | 0.77 | AKR1C3 (0.48) | HSD11B1 | |
| SCHEMBL8434832 | 0.76 | HSD11B1 (0.44) | HSD11B1ALDH1A1MAPTKDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2123652-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2009-11-25 | — | — | EP | disclosed |