Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.66 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.66 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.53 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | F13A1 | P00488 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | CA4 | P22748 | 2/20 | 0.46 |
| ▸ | CA6 | P23280 | 2/20 | 0.46 |
| ▸ | CA5A | P35218 | 2/20 | 0.46 |
| ▸ | THPO | P40225 | 2/20 | 0.46 |
| ▸ | CA7 | P43166 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.46 |
| ▸ | CASP2 | P42575 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10151331 | 0.93 | KEAP1 (0.70) | SMN1; SMN2KEAP1PAOXACE2CYP2C19 | |
| SCHEMBL11934970 | 0.89 | SMN1; SMN2 (0.66) | SMN1; SMN2KEAP1PAOXACE2CYP2C19 | |
| SCHEMBL13045709 | 0.89 | SMN1; SMN2 (0.66) | SMN1; SMN2KEAP1PAOXACE2CYP2C19 | |
| SCHEMBL8310938 | 0.89 | KEAP1 (0.64) | SMN1; SMN2KEAP1PAOXACE2CYP2C19 | |
| SCHEMBL4398803 | 0.89 | PAOX (0.62) | SMN1; SMN2KEAP1PAOXCYP2C19CA12 | |
| SCHEMBL8310330 | 0.87 | KEAP1 (0.67) | SMN1; SMN2KEAP1PAOXACE2CYP2C19 | |
| SCHEMBL8875699 | 0.85 | ACE2 (0.64) | SMN1; SMN2KEAP1ACE2CYP2C19CA12 | |
| SCHEMBL721355 | 0.82 | PAOX (0.64) | SMN1; SMN2KEAP1PAOXCYP2C19CA12 | |
| SCHEMBL179978 | 0.82 | KEAP1 (0.86) | SMN1; SMN2KEAP1HPGDDUSP3GAA | |
| SCHEMBL8309741 | 0.81 | ACE2 (0.72) | SMN1; SMN2KEAP1PAOXACE2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1569694-B1 | POLYAMINE CONJUGATES WITH ACIDIC RETINOIDS AND PREPARATION THEREOF | PAPAIOANNOU DIONYSIOS (GR) | 2009-11-25 | — | — | EP | disclosed |