Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.72 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 2/20 | 0.47 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8310938 | 0.92 | KEAP1 (0.64) | ACE2KEAP1SMN1; SMN2HPGDDUSP3 | |
| SCHEMBL8310330 | 0.90 | KEAP1 (0.67) | ACE2KEAP1SMN1; SMN2HPGDDUSP3 | |
| SCHEMBL4401738 | 0.89 | CA12 (0.53) | ACE2KEAP1SMN1; SMN2HPGDDUSP3 | |
| SCHEMBL1690928 | 0.84 | — | — | |
| SCHEMBL12921297 | 0.84 | ACE2 (1.00) | ACE2KEAP1SMN1; SMN2CA12CA9 | |
| SCHEMBL10151331 | 0.84 | KEAP1 (0.70) | ACE2KEAP1SMN1; SMN2HPGDDUSP3 | |
| SCHEMBL2570372 | 0.82 | ACE2 (0.95) | ACE2KEAP1SMN1; SMN2CA12CA9 | |
| SCHEMBL11934970 | 0.81 | SMN1; SMN2 (0.66) | ACE2KEAP1SMN1; SMN2HPGDDUSP3 | |
| SCHEMBL13045709 | 0.81 | SMN1; SMN2 (0.66) | ACE2KEAP1SMN1; SMN2HPGDDUSP3 | |
| SCHEMBL13636974 | 0.81 | SMN1; SMN2 (0.66) | ACE2KEAP1SMN1; SMN2HPGDDUSP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119019346-A | Heterocyclic polyamine compound, preparation method and application thereof, and heterocyclic polyamine combined solution | 大连理工大学 | 2024-11-26 | — | — | CN | disclosed |
| EP-3267794-B1 | BIARYLTRIAZOLE INHIBITORS OF MACROPHAGE MIGRATION INHIBITORY FACTOR | UNIV YALE (US) | 2020-09-09 | — | — | EP | disclosed |
| US-20170002252-A1 | Lubricant Compositions and Methods of Making and Using Same | EXXONMOBIL CHEMICAL PATENTS INC. | 2017-01-05 | — | — | US | disclosed |
| EP-0790986-B1 | ANILINE DERIVATIVES | ZENECA LTD (GB) | 1999-01-20 | — | — | EP | disclosed |
| US-5561139-A | IMMUNOSUPPRESSANTS; SIDE EFFECT REDUCTION | ABBOTT LABORATORIES (US) | 1996-10-01 | — | — | US | disclosed |
| US-5530120-A | ANALOGS OF ASCOMYCIN AND FK-506 AS IMMUNOSUPPRESSANTS AND-MODULATORS; SIDE EFFECT REDUCTION | ABBOTT LABORATORIES (US) | 1996-06-25 | — | — | US | disclosed |
| WO-1994021634-A1 | SUBSTITUTED ALICYCLIC-ALIPHATIC AMINE-CONTAINING MACROCYCLIC IMMUNOMODULATORS | ABBOTT LABORATORIES (US) | 1994-09-29 | — | — | WO | disclosed |
| US-4851524-A | SLUDGE DISPERSANTS | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1989-07-25 | — | — | US | disclosed |
| US-4820738-A | ANTITUMOR AGENTS; CHELATING AGENTS; GROWTH INHIBITORS; LEUKEMIA | AMERICAN CYANAMID COMPANY (US) | 1989-04-11 | — | — | US | disclosed |
| US-4614618-A | CHELATING AGENTS AND ANTICANCER AGENTS | AMERICAN CYANAMID COMPANY (US) | 1986-09-30 | — | — | US | disclosed |
| US-4526989-A | And ascorbic acid salt | AMERICAN CYANAMID COMPANY (US) | 1985-07-02 | — | — | US | disclosed |
| US-4456552-A | CHELATION, ANTITUMOR | AMERICAN CYANAMID COMPANY (US) | 1984-06-26 | — | — | US | disclosed |
| US-4430501-A | CHELATION, ANTITUMOR, COMPLEXING, SEQUESTERING | AMERICAN CYANAMID COMPANY (US) | 1984-02-07 | — | — | US | disclosed |
| EP-0037486-B1 | METAL CHELATES OF 1,4-BIS(SUBSTITUTED-AMINO)-5,8-DIHYDROXY-ANTHRAQUINONES | AMERICAN CYANAMID COMPANY (US) | 1984-01-25 | — | — | EP | disclosed |
| EP-0021622-B1 | 1-(AMINOALKYLAMINO)-5,8-DIHYDROXY-4-SUBSTITUTED-ANTHRAQUINONES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | AMERICAN CYANAMID COMPANY (US) | 1982-10-20 | — | — | EP | disclosed |
| US-4296030-A | ANTITUMOR AGENTS, DYES | AMERICAN CYANAMID COMPANY (US) | 1981-10-20 | — | — | US | disclosed |
| EP-0037486-A2 | Metal chelates of 1,4-bis(substituted-amino)-5,8-dihydroxy-anthraquinones | AMERICAN CYANAMID COMPANY (US) | 1981-10-14 | — | — | EP | disclosed |
| US-4278689-A | ANTITUMOR AGENTS | AMERICAN CYANAMID COMPANY (US) | 1981-07-14 | — | — | US | disclosed |
| EP-0021622-A1 | 1-(Aminoalkylamino)-5,8-dihydroxy-4-substituted-anthraquinones, process for their preparation and pharmaceutical compositions containing them | AMERICAN CYANAMID COMPANY (US) | 1981-01-07 | — | — | EP | disclosed |
| US-4197249-A | ANTITUMOR AGENTS | AMERICAN CYANAMID COMPANY (US) | 1980-04-08 | — | — | US | disclosed |