Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.34 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6943323 | 0.86 | TSHR (0.48) | TSHRALOX15RORCHDAC4HDAC2 | |
| SCHEMBL25274613 | 0.85 | CA1 (0.45) | ALOX15ALOX12AMY1AHSPA5GABRA1 | |
| SCHEMBL12457769 | 0.83 | HTT (0.38) | TSHRALOX15RORCSMN1; SMN2ALDH1A1 | |
| SCHEMBL8760785 | 0.81 | TSHR (0.44) | TSHRALOX15RORCHDAC4HDAC2 | |
| SCHEMBL14557201 | 0.81 | TSHR (0.44) | TSHRALOX15RORCHDAC4HDAC2 | |
| SCHEMBL4549116 | 0.81 | CA1 (0.50) | TSHRRORCGABRA1GABRB2HIF1A | |
| SCHEMBL12457777 | 0.78 | AMY1A (0.41) | TSHRRORCAMY1AHSPA5CYP2C9 | |
| SCHEMBL14344951 | 0.78 | CA1 (0.47) | TSHRALOX15ALOX12RORCHDAC4 | |
| SCHEMBL310746 | 0.77 | ERN1 (0.58) | TSHRRORC | |
| SCHEMBL45859 | 0.77 | GABRA1 (0.52) | ALOX15ALOX12AMY1AHSPA5GABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2123312-A2 | Extraction of solvents from drug containing polymer reservoirs | Cordis Corporation (US) | 2009-11-25 | — | — | EP | disclosed |
| EP-2042202-A2 | Local vascular delivery of mTor inhibitors in combination with peroxisome proliferators-activated receptor stimulators | Cordis Corporation (US) | 2009-04-01 | — | — | EP | disclosed |