SCHEMBL1363728

SCHEMBL1363728

c1cnc2nsnc2c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29358342 0.74 ALDH1A1 (0.55)
SCHEMBL88611 0.74 ALDH1A1 (0.55)
SCHEMBL29408294 0.74 ALDH1A1 (0.55)
Ethyne SCHEMBL27784530 0.70 ALDH1A1 (0.50)
SCHEMBL4403016 0.70
Benzo[1,2,5]Thiadiazole SCHEMBL21874941 0.70 MAPT (0.50)
Benzo[1,2,5]Thiadiazole SCHEMBL15512538 0.70
Benzo[1,2,5]Thiadiazole SCHEMBL20886 0.70
Benzo[1,2,5]Thiadiazole SCHEMBL30785348 0.68 MAPT (0.48)
SCHEMBL8194 0.67 ALDH1A1 (0.67)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 114 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9328203-B2 Benzodithiophene based copolymer containing pyridino [2,1,3] thiadiazole units and preparing method and applications thereof OCEAN'S KING LIGHTING SCIENCE & TECHNOLOGY CO., LTD. (CN) 2016-05-03 US claimed
US-20150284505-A1 BENZODITHIOPHENE BASED COPOLYMER CONTAINING PYRIDINO [2,1,3] THIADIAZOLE UNITS AND PREPARING METHOD AND APPLICATIONS THEREOF OCEAN'S KING LIGHTING SCIENCE & TECHNOLOGY CO., LTD. (CN) 2015-10-08 US claimed
US-20110288253-A1 MULTI-COLORED CONJUGATED POLYMERS WITH HIGHLY TRANSMISSIVE OXIDIZED STATE UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2011-11-24 US claimed
US-20240368173-A1 TRICYCLIC GPR65 MODULATORS Pathios Therapeutics Limited (GB) 2024-11-07 US disclosed
EP-4219465-A2 PRMT5 INHIBITORS AND USES THEREOF Epizyme Inc (US) 2023-08-02 EP disclosed
CN-115974900-A Polycyclic aromatic compound, polymer compound, composition, material, light-emitting element, display device, and lighting device 学校法人关西学院 2023-04-18 CN disclosed
CN-115974899-A Polycyclic aromatic compound, material for organic device, organic electroluminescent element, display device, and lighting device 学校法人关西学院 2023-04-18 CN disclosed
CN-115894535-A Polycyclic aromatic compound, multimer thereof, material for organic device, organic electroluminescent element, and application thereof 学校法人关西学院 2023-04-04 CN disclosed
CN-115894533-A Polycyclic aromatic compound, material for organic device, organic electroluminescent element, display device, and lighting device 学校法人关西学院 2023-04-04 CN disclosed
CN-115873003-A Polycyclic aromatic compound, material for organic device, organic electroluminescent element, display device, and lighting device 爱思开新材料捷恩智株式会社 2023-03-31 CN disclosed
CN-115819444-A Polycyclic aromatic compound, organic electroluminescent element, display device, and lighting device 学校法人关西学院 2023-03-21 CN disclosed
WO-2014100734-A1 PRMT5 INHIBITORS AND USES THEREOF Epizyme, Inc. (US) 2014-06-26 WO disclosed
WO-2014082309-A1 BENZODITHIOPHENE BASED COPOLYMER CONTAINING PYRIDINO [2,1,3] THIADIAZOLE UNITS AND PREPARING METHOD AND APPLICATIONS THEREOF 海洋王照明科技股份有限公司 (CN) 2014-06-05 WO disclosed
US-20110183988-A1 COMPOUNDS AND METHODS FOR KINASE MODULATION, AND INDICATIONS THEREFOR PLEXXIKON INC. 2011-07-28 US disclosed
US-20110009394-A1 TRICYCLIC NITROGEN COMPOUNDS AND THEIR USE AS ANTIBACTERIAL AGENTS GLAXO GROUP LIMITED (GB) 2011-01-13 US disclosed
WO-2010046388-A1 SUBSTITUTED (AZA) -1-METHYL-1H-QUINOLIN-2-ONES AS ANTIBACTERIALS GLAXO GROUP LIMITED (GB) 2010-04-29 WO disclosed
WO-2010043714-A1 TRICYCLIC NITROGEN COMPOUNDS USED AS ANTIBACTERIALS GLAXO GROUP LIMITED (GB) 2010-04-22 WO disclosed
WO-2009087153-A1 TRICYCLIC NITROGEN COMPOUNDS AND THEIR USE AS ANTIBACTERIAL AGENTS GLAXO GROUP LIMITED (GB) 2009-07-16 WO disclosed
US-20070027156-A1 Crf antagonists and heterobicyclic compounds ONO PHARMACEUTICAL CO., LTD. (JP) 2007-02-01 US disclosed
US-20070027156-A1 Crf antagonists and heterobicyclic compounds ONO PHARMACEUTICAL CO., LTD. (JP) 2007-02-01 US disclosed