Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | SMO | Q99835 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | OXTR | P30559 | 3/20 | 0.37 |
| ▸ | ERN1 | O75460 | 3/20 | 0.37 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.35 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13637630 | 0.87 | PTGS2 (0.46) | PTGS2PTGS1MEN1KMT2A | |
| SCHEMBL13212812 | 0.87 | MEN1 (0.43) | PTGS2PTGS1MEN1KMT2AERN1 | |
| SCHEMBL13213178 | 0.86 | ERN1 (0.42) | PTGS2PTGS1MEN1KMT2AOXTR | |
| SCHEMBL13637334 | 0.86 | MEN1 (0.52) | PTGS2PTGS1MEN1KMT2AOXTR | |
| SCHEMBL13212839 | 0.83 | MDM2 (0.51) | PTGS2PTGS1MEN1KMT2A | |
| SCHEMBL14529327 | 0.83 | ERN1 (0.40) | PTGS2PTGS1MEN1KMT2AOXTR | |
| SCHEMBL2916511 | 0.81 | RPA1 (0.54) | — | |
| SCHEMBL13213071 | 0.80 | MEN1 (0.43) | PTGS2PTGS1MEN1KMT2AOXTR | |
| SCHEMBL13213106 | 0.80 | CA9 (0.44) | PTGS2MEN1KMT2A | |
| SCHEMBL2917961 | 0.80 | CA9 (0.54) | PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622471-B2 | Pyrazole derivatives having a pyridazine and pyridine functionality | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2009-11-24 | — | — | US | disclosed |