Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 20/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2913285 | 0.88 | KDM1A (0.50) | KDM1A | |
| SCHEMBL2916474 | 0.84 | KDM4E (0.50) | KDM1A | |
| SCHEMBL13637534 | 0.84 | KDM1A (0.51) | KDM1A | |
| SCHEMBL2921273 | 0.82 | MGLL (0.51) | KDM1A | |
| SCHEMBL2911623 | 0.82 | MGLL (0.56) | KDM1A | |
| SCHEMBL2920781 | 0.81 | PTGS2 (0.64) | — | |
| SCHEMBL13212922 | 0.81 | PTGS2 (0.49) | KDM1A | |
| Hydrochloric Acid SCHEMBL2919880 | 0.80 | PTGS2 (0.49) | KDM1A | |
| SCHEMBL2915459 | 0.79 | PTGS2 (0.48) | KDM1A | |
| Hydrochloric Acid SCHEMBL2912049 | 0.79 | PTGS2 (0.47) | KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622471-B2 | Pyrazole derivatives having a pyridazine and pyridine functionality | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2009-11-24 | — | — | US | disclosed |