Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | PRNP | P04156 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 4/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | LDHA | P00338 | 1/20 | 0.37 |
| ▸ | LDHB | P07195 | 1/20 | 0.37 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methane SCHEMBL16742564 | 0.98 | ALDH1A1 (0.44) | ALDH1A1TSHRKDM4ELMNAHPGD | |
| Urea SCHEMBL23160877 | 0.81 | ALDH1A1 (0.52) | ALDH1A1TSHRKDM4ELMNAHPGD | |
| SCHEMBL20830186 | 0.81 | ALDH1A1 (0.42) | ALDH1A1KDM4ELMNAHPGDPRNP | |
| SCHEMBL17664006 | 0.81 | ALDH1A1 (0.42) | ALDH1A1KDM4ELMNAHPGDPRNP | |
| SCHEMBL86396 | 0.80 | KDM4E (0.52) | ALDH1A1TSHRKDM4ELMNAHPGD | |
| SCHEMBL17495564 | 0.80 | KDM4E (0.52) | ALDH1A1TSHRKDM4ELMNAHPGD | |
| SCHEMBL13524319 | 0.78 | ALDH1A1 (0.45) | ALDH1A1TSHRKDM4ELMNAHPGD | |
| SCHEMBL3384529 | 0.78 | ALDH1A1 (0.45) | ALDH1A1TSHRKDM4ELMNAHPGD | |
| SCHEMBL28611785 | 0.78 | ALDH1A1 (0.45) | ALDH1A1TSHRKDM4ELMNAHPGD | |
| SCHEMBL11805964 | 0.78 | ALDH1A1 (0.45) | ALDH1A1TSHRKDM4ELMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-11066398-B2 | Small molecule c-Myc inhibitors | THE SCRIPPS RESEARCH INSTITUTE (US) | 2021-07-20 | — | — | US | disclosed |
| EP-3257845-A1 | PREPARATION OF 2,5-FURANDICARBOXYLIC ACID BY OXIDATION OF 5-(ACETOXYMETHYL)FURFURAL IN THE PRESENCE OF A BROMIDE, OXYGEN AND A COBALT(II) OR CERIUM(III) CATALYST | Archer Daniels Midland Company (US) | 2017-12-20 | — | — | EP | disclosed |
| CN-106456616-A | Small molecule C-Myc inhibitors | 斯克利普斯研究院 | 2017-02-22 | — | — | CN | disclosed |
| EP-3082812-A1 | SMALL MOLECULE C-MYC INHIBITORS | The Scripps Research Institute (US) | 2016-10-26 | — | — | EP | disclosed |
| US-20160264560-A1 | SMALL MOLECULE C-MYC INHIBITORS | SORRENTO THERAPEUTICS, INC. | 2016-09-15 | — | — | US | disclosed |
| US-20150368411-A1 | POLYMERS, SUBSTRATES, METHODS FOR MAKING SUCH, AND DEVICES COMPRISING THE SAME | AVERTICA INC. | 2015-12-24 | — | — | US | disclosed |
| WO-2015089180-A1 | SMALL MOLECULE C-MYC INHIBITORS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2015-06-18 | — | — | WO | disclosed |
| EP-2548902-A1 | Composition and method for improving adhesion of textile substrates to rubber and articles resulting therefrom | Milliken & Company (US) | 2013-01-23 | — | — | EP | disclosed |
| US-7619092-B2 | Piperidine compounds | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-11-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160264560-A1 | SMALL MOLECULE C-MYC INHIBITORS | MYC, MYCBP, MYCBP2 | ALDH1A1 3976/4885TSHR 4300/4885KDM4E 931/4885 |
| US-11066398-B2 | Small molecule c-Myc inhibitors | MYC, MYCBP, MYCBP2 | ALDH1A1 3976/4885TSHR 4300/4885KDM4E 931/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.