Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 10/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13637647 | 0.89 | TRPV1 (0.40) | RORCTRPV1NR1H4PTPN1ABCB1 | |
| SCHEMBL13637720 | 0.87 | RORC (0.38) | RORCTRPV1NR1H4PTPN1ABCB1 | |
| SCHEMBL13637718 | 0.87 | RORC (0.38) | RORCTRPV1NR1H4PTPN1 | |
| SCHEMBL13637475 | 0.85 | RORC (0.38) | RORCTRPV1NR1H4PTPN1 | |
| SCHEMBL13637788 | 0.85 | TRPV1 (0.38) | RORCTRPV1NR1H4PTPN1ABCB1 | |
| SCHEMBL13637675 | 0.85 | TRPV1 (0.42) | RORCTRPV1PTPN1 | |
| SCHEMBL13637591 | 0.84 | RORC (0.39) | RORCTRPV1NR1H4PTPN1GPBAR1 | |
| SCHEMBL13637470 | 0.84 | RORC (0.39) | RORCTRPV1NR1H4PTPN1GPBAR1 | |
| SCHEMBL13628402 | 0.84 | RORC (0.57) | RORCTRPV1PTPN1GPBAR1 | |
| SCHEMBL13637724 | 0.83 | TRPV1 (0.41) | RORCTRPV1NR1H4PTPN1GPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090275583-A1 | ANTIVIRAL COMPOUNDS AND USE THEREOF | MYRIAD GENETICS, INCORPORATED (US) | 2009-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090275583-A1 | ANTIVIRAL COMPOUNDS AND USE THEREOF | MAVS, ZC3HAV1, EIF2AK2 | RORC 514/4885TRPV1 3411/4885NR1H4 1225/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.