SCHEMBL13637909

SCHEMBL13637909

Cc1cccc2c1sc1c(C)cc3ccccc3c12

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.45
CYP2A6 P11509 5/20 0.45
CYP1A2 P05177 8/20 0.44
HPGD P15428 5/20 0.44
HSD17B10 Q99714 5/20 0.44
MAPT P10636 3/20 0.39
KDM4E B2RXH2 2/20 0.39
L3MBTL1 Q9Y468 4/20 0.36
LMNA P02545 2/20 0.36
POLB P06746 2/20 0.36
HCRTR1 O43613 1/20 0.36
TSHR P16473 4/20 0.35
HIF1A Q16665 3/20 0.35
MAPK1 P28482 2/20 0.35
CASP1 P29466 2/20 0.35
CYP3A4 P08684 2/20 0.35
RAB9A P51151 2/20 0.35
ERBB2 P04626 1/20 0.35
FYN P06241 1/20 0.35
MAOA P21397 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18810717 0.84 HSD17B10 (0.46) ALDH1A1CYP2A6CYP1A2HPGDHSD17B10
SCHEMBL23348346 0.82 ADORA3 (0.42) ALDH1A1CYP2A6CYP1A2HPGDHSD17B10
SCHEMBL23348348 0.82 LIMK1 (0.43) ALDH1A1CYP2A6CYP1A2HPGDHSD17B10
SCHEMBL16283926 0.82 ALDH1A1 (0.46) ALDH1A1CYP2A6CYP1A2HPGDHSD17B10
SCHEMBL18810729 0.79 CYP1A2 (0.39) ALDH1A1CYP2A6CYP1A2HPGDHSD17B10
SCHEMBL23348262 0.77 CYP1A2 (0.42) ALDH1A1CYP2A6CYP1A2HPGDHSD17B10
SCHEMBL23348349 0.77 CYP1A2 (0.35) ALDH1A1CYP2A6CYP1A2HPGDHSD17B10
SCHEMBL23348347 0.77 PSMB5 (0.35) ALDH1A1CYP2A6CYP1A2HPGDHSD17B10
SCHEMBL21449415 0.77 MAPT (0.50) ALDH1A1CYP2A6CYP1A2HPGDHSD17B10
SCHEMBL18810714 0.76 ALDH1A1 (0.42) ALDH1A1CYP2A6CYP1A2HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7615145-B2 One-pot process for the reduction of sulfur, nitrogen and the production of useful oxygenates from hydrocarbon materials via one-pot selective oxidation KOCAT INC. (KR) 2009-11-10 US disclosed
US-7591943-B2 desulfurization, denitrification and producing hydrocarbon oxidates by reacting with oxidant in presence of homogeneous oxidation catalyst and hydrobromide mixtures; gasoline with improved oxidant rating, cetane number KOCAT INC. (KR) 2009-09-22 US disclosed
US-20080149533-A1 ONE-POT PROCESS FOR THE REDUCTION OF SULFUR, NITROGEN AND THE PRODUCTION OF USEFUL OXYGENATES FROM HYDROCARBON MATERIALS VIA ONE-POT SELECTIVE OXIDATION KOCAT INC. (KR) 2008-06-26 US disclosed
US-20080121565-A1 PROCESS FOR THE REDUCTION OF SULFUR, NITROGEN AND THE PRODUCTION OF USEFUL OXYGENATES FROM HYDROCARBON MATERIALS VIA ONE-POT SELECTIVE OXIDATION KOCAT INC. (KR) 2008-05-29 US disclosed
EP-1911830-A1 Process for the reduction of sulfur, nitrogen and the production of useful oxygenates from hydrocarbon materials via one-pot selective oxidation Kocat Inc. (KR) 2008-04-16 EP disclosed
EP-1911831-A1 One-pot process for the reduction of sulfur, nitrogen and the production of useful oxygenates from hydrocarbon materials via one-pot selective oxidation Kocat Inc. (KR) 2008-04-16 EP disclosed