Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 7/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 7/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13633343 | 0.88 | KCNH2 (0.46) | MTNR1AMTNR1BKCNH2SIRT2 | |
| SCHEMBL3572910 | 0.88 | KCNH2 (0.46) | MTNR1AMTNR1BKCNH2SIRT2 | |
| SCHEMBL3572912 | 0.81 | MTNR1A (0.38) | MTNR1AMTNR1BKCNH2 | |
| SCHEMBL20679509 | 0.79 | MTNR1A (0.43) | MTNR1AMTNR1BKCNH2 | |
| SCHEMBL6668585 | 0.74 | KCNH2 (0.58) | KCNH2 | |
| Hydrochloric Acid SCHEMBL5745883 | 0.73 | KCNH2 (0.61) | KCNH2 | |
| SCHEMBL5263873 | 0.72 | KCNH2 (0.52) | KCNH2 | |
| SCHEMBL5253266 | 0.72 | KCNH2 (0.59) | KCNH2 | |
| SCHEMBL5253262 | 0.72 | KCNH2 (0.59) | KCNH2 | |
| SCHEMBL5253263 | 0.72 | KCNH2 (0.59) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622481-B2 | Antibacterial compounds | GLAXO GROUP LIMITED (GB) | 2009-11-24 | — | — | US | disclosed |