Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.37 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.37 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 6/20 | 0.34 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.34 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.33 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9922579 | 0.94 | P2RY12 (0.43) | KMT2APPARGRAB9ARXFP1NR2E3 | |
| SCHEMBL13638511 | 0.88 | P2RY12 (0.45) | PPARGRAB9ARXFP1NR2E3NCOR2 | |
| SCHEMBL12177240 | 0.87 | KMT2A (0.40) | KMT2APPARGP2RY12ALDH1A1NOD1 | |
| SCHEMBL13638605 | 0.87 | KMT2A (0.38) | KMT2APPARGP2RY12ALDH1A1NOD1 | |
| SCHEMBL12177306 | 0.86 | KMT2A (0.39) | KMT2APPARGP2RY12ALDH1A1NOD1 | |
| SCHEMBL12177332 | 0.85 | KMT2A (0.39) | KMT2APPARGP2RY12ALDH1A1NOD1 | |
| SCHEMBL13638708 | 0.85 | P2RY12 (0.40) | KMT2APPARGRAB9ARXFP1NR2E3 | |
| SCHEMBL13638699 | 0.85 | P2RY12 (0.47) | KMT2APPARGRAB9ARXFP1NR2E3 | |
| SCHEMBL12177266 | 0.85 | KMT2A (0.37) | KMT2APPARGP2RY12ALDH1A1NOD1 | |
| SCHEMBL13182847 | 0.84 | KMT2A (0.38) | KMT2APPARGP2RY12ALDH1A1NOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622474-B2 | Asulfonyl(urea, thiourea, guanidine, cyanoguanidine) compounds; cardiovascular disorders; thrombosis | PORTOLA PHARMACEUTICALS, INC. (US) | 2009-11-24 | — | — | US | disclosed |