Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KIT | P10721 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13638632 | 0.93 | P2RY12 (0.42) | P2RY12MEN1KMT2AKITCA12 | |
| SCHEMBL13633801 | 0.92 | P2RY12 (0.47) | P2RY12MEN1KMT2A | |
| SCHEMBL9922990 | 0.85 | P2RY12 (0.51) | P2RY12MEN1KMT2ACA12CA9 | |
| SCHEMBL12161667 | 0.83 | P2RY12 (0.49) | P2RY12MEN1KMT2ACA12CA9 | |
| SCHEMBL9922995 | 0.81 | P2RY12 (0.48) | P2RY12MEN1KMT2A | |
| SCHEMBL14228344 | 0.80 | P2RY12 (0.47) | P2RY12MEN1KMT2A | |
| SCHEMBL9922992 | 0.80 | P2RY12 (0.47) | P2RY12MEN1KMT2ACA9 | |
| SCHEMBL12177675 | 0.80 | P2RY12 (0.41) | P2RY12MEN1KMT2AKITCA12 | |
| SCHEMBL13633802 | 0.78 | P2RY12 (0.43) | P2RY12MEN1KMT2A | |
| SCHEMBL9922112 | 0.78 | P2RY12 (0.53) | P2RY12MEN1KMT2ACA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622474-B2 | Asulfonyl(urea, thiourea, guanidine, cyanoguanidine) compounds; cardiovascular disorders; thrombosis | PORTOLA PHARMACEUTICALS, INC. (US) | 2009-11-24 | — | — | US | disclosed |