Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 18/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | TERT | O14746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12177083 | 0.90 | MEN1 (0.31) | ATMTERT | |
| SCHEMBL13638646 | 0.87 | ATM (0.42) | ATM | |
| SCHEMBL9922888 | 0.81 | P2RY12 (0.47) | ATM | |
| SCHEMBL9922335 | 0.80 | P2RY12 (0.30) | — | |
| SCHEMBL12177643 | 0.79 | ATM (0.35) | ATM | |
| SCHEMBL13638585 | 0.76 | TERT (0.35) | ATMTERT | |
| SCHEMBL13638542 | 0.72 | PPARG (0.39) | — | |
| SCHEMBL9922887 | 0.71 | P2RY12 (0.49) | — | |
| SCHEMBL12161275 | 0.71 | P2RY12 (0.42) | — | |
| SCHEMBL14228346 | 0.71 | P2RY12 (0.39) | EPHX2TERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622474-B2 | Asulfonyl(urea, thiourea, guanidine, cyanoguanidine) compounds; cardiovascular disorders; thrombosis | PORTOLA PHARMACEUTICALS, INC. (US) | 2009-11-24 | — | — | US | disclosed |