Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13638646 | 0.91 | ATM (0.42) | ATM | |
| SCHEMBL13638373 | 0.83 | ATM (0.37) | ATMWEE1 | |
| SCHEMBL12161374 | 0.83 | P2RY12 (0.40) | ATMWEE1 | |
| SCHEMBL13638703 | 0.79 | ATM (0.34) | ATM | |
| SCHEMBL13638585 | 0.78 | TERT (0.35) | ATM | |
| SCHEMBL12177083 | 0.77 | MEN1 (0.31) | ATM | |
| SCHEMBL13182848 | 0.75 | HRH3 (0.40) | — | |
| SCHEMBL9922536 | 0.74 | P2RY12 (0.42) | WEE1 | |
| SCHEMBL12161316 | 0.74 | P2RY12 (0.46) | ATM | |
| SCHEMBL13638705 | 0.73 | ATM (0.43) | ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8067428-B2 | Platelet ADP receptor inhibitors | PORTOLA PHARMACEUTICALS, INC. (US) | 2011-11-29 | — | — | US | disclosed |
| US-20100234350-A1 | PLATELET ADP RECEPTOR INHIBITORS | PORTOLA PHARMACEUTICALS, INC. (US) | 2010-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100234350-A1 | PLATELET ADP RECEPTOR INHIBITORS | TBXA2R, GP6, P2RY6 | ATM 1908/4885WEE1 3307/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.