Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9969436 | 0.81 | ALDH1A1 (0.51) | ALDH1A1KDM4EMAPTCYP3A4TSHR | |
| SCHEMBL16788783 | 0.81 | ALDH1A1 (0.51) | ALDH1A1KDM4EMAPTCYP3A4TSHR | |
| SCHEMBL12939649 | 0.81 | ALDH1A1 (0.51) | ALDH1A1KDM4EMAPTCYP3A4TSHR | |
| SCHEMBL14681197 | 0.80 | CA9 (0.42) | ALDH1A1KDM4EMAPTCYP3A4TSHR | |
| SCHEMBL18177878 | 0.79 | ALDH1A1 (0.62) | ALDH1A1KDM4EMAPTCYP3A4TSHR | |
| SCHEMBL15219723 | 0.74 | ALDH1A1 (0.41) | ALDH1A1TSHRHPGDHSD17B10ACHE | |
| SCHEMBL18697147 | 0.74 | — | — | |
| SCHEMBL16788791 | 0.73 | LOXL2 (0.44) | ALDH1A1KDM4ETSHRCYP1A2HPGD | |
| SCHEMBL23376909 | 0.73 | — | — | |
| SCHEMBL14255416 | 0.73 | ACACB (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304079-B2 | ANISOTROPIC UNITS ; POSITIVE BIREFRINGEMENT; SOLUTION CASTING; | AKRON POLYMER SYSTEMS (US) | 2012-11-06 | — | — | US | disclosed |
| US-20080241565-A1 | Optical compensation films with birefringence enhancing substituents for liquid crystal display | AKRON POLYMER SYSTEMS | 2008-10-02 | — | — | US | disclosed |