Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SCD | O00767 | 2/20 | 0.36 |
| ▸ | SCD5 | Q86SK9 | 2/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.36 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | TNK1 | Q13470 | 1/20 | 0.36 |
| ▸ | PIN1 | Q13526 | 3/20 | 0.35 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.35 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13638824 | 0.95 | KMT2A (0.39) | PDCD1CD274GRM2KMT2ASCD | |
| SCHEMBL2770055 | 0.95 | PARP1 (0.38) | KMT2ASCDSCD5MCHR1ACKR3 | |
| SCHEMBL13638912 | 0.93 | KMT2A (0.47) | KMT2A | |
| SCHEMBL13639003 | 0.92 | PIN1 (0.37) | KMT2ASCDSCD5PIN1HPGD | |
| SCHEMBL13638771 | 0.92 | SCD (0.36) | PDCD1CD274KMT2ASCDSCD5 | |
| SCHEMBL13638833 | 0.92 | GRM2 (0.39) | PDCD1CD274GRM2SCDSCD5 | |
| SCHEMBL13639001 | 0.92 | KMT2A (0.38) | PDCD1CD274GRM2KMT2ASCD | |
| SCHEMBL2770243 | 0.92 | KMT2A (0.38) | PDCD1CD274GRM2KMT2ASCD | |
| SCHEMBL2770504 | 0.92 | PIN1 (0.37) | KMT2ASCDSCD5PIN1HPGD | |
| SCHEMBL2770606 | 0.92 | PIN1 (0.37) | KMT2ASCDSCD5PIN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |