Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13638749 | 0.90 | KMT2A (0.54) | KMT2AKDM4ETDP1LMNATP53 | |
| SCHEMBL13162031 | 0.86 | KMT2A (0.69) | KMT2AKDM4ETDP1TSHRLMNA | |
| SCHEMBL13162599 | 0.85 | KMT2A (0.68) | KMT2AKDM4ETDP1TSHRLMNA | |
| SCHEMBL13638972 | 0.84 | KMT2A (0.46) | KMT2AKDM4ETDP1LMNANPC1 | |
| SCHEMBL13163150 | 0.82 | KMT2A (0.64) | KMT2AKDM4ETDP1TSHRLMNA | |
| SCHEMBL13162819 | 0.81 | KMT2A (0.63) | KMT2AKDM4ELMNANPC1RAB9A | |
| SCHEMBL13164020 | 0.80 | KMT2A (0.60) | KMT2AKDM4ETSHRLMNANPC1 | |
| SCHEMBL30230078 | 0.80 | KMT2A (0.64) | KMT2AKDM4ETDP1TSHRLMNA | |
| SCHEMBL13164022 | 0.77 | KMT2A (0.56) | KMT2AKDM4ETSHRLMNANPC1 | |
| SCHEMBL13162387 | 0.75 | KMT2A (0.57) | KMT2ATDP1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |