Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | JAK1 | P23458 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.36 |
| ▸ | WNT3A | P56704 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13162600 | 0.88 | KMT2A (0.49) | KMT2AGRM2JAK2JAK1HPGD | |
| SCHEMBL13162385 | 0.87 | KMT2A (0.48) | KMT2AGRM2JAK2JAK1HPGD | |
| SCHEMBL13638849 | 0.84 | KMT2A (0.65) | KMT2ALMNATDP1KDM4EALDH1A1 | |
| SCHEMBL13638749 | 0.79 | KMT2A (0.54) | KMT2ALMNATDP1KDM4EALDH1A1 | |
| SCHEMBL13634408 | 0.78 | GRM2 (0.43) | KMT2AGRM2JAK2JAK1HPGD | |
| SCHEMBL13638850 | 0.78 | KMT2A (0.42) | KMT2AGRM2JAK2JAK1LMNA | |
| SCHEMBL13634813 | 0.77 | KMT2A (0.41) | KMT2AGRM2JAK2JAK1HPGD | |
| SCHEMBL13638816 | 0.77 | IRAK4 (0.46) | KMT2AGRM2JAK2JAK1HPGD | |
| SCHEMBL15888568 | 0.76 | LMNA (0.44) | KMT2AHPGDLMNATDP1ALDH1A1 | |
| SCHEMBL13638768 | 0.76 | IRAK4 (0.46) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |