Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13638849 | 0.90 | KMT2A (0.65) | KMT2ATDP1LMNAALDH1A1KDM4E | |
| SCHEMBL13162387 | 0.86 | KMT2A (0.57) | KMT2ATDP1LMNAALDH1A1POLB | |
| SCHEMBL13638750 | 0.85 | KMT2A (0.56) | KMT2ATDP1LMNACYP2C9CYP2C19 | |
| SCHEMBL13270661 | 0.82 | KMT2A (0.59) | KMT2ATDP1LMNACYP2C19ALDH1A1 | |
| SCHEMBL13638972 | 0.79 | KMT2A (0.46) | KMT2ATDP1LMNAALDH1A1KDM4E | |
| SCHEMBL13162031 | 0.75 | KMT2A (0.69) | KMT2ATDP1LMNAKDM4EPOLB | |
| SCHEMBL13162599 | 0.74 | KMT2A (0.68) | KMT2ATDP1LMNAALDH1A1KDM4E | |
| SCHEMBL15888559 | 0.74 | HTR4 (0.51) | KMT2ATDP1HRH3ALDH1A1CYP2D6 | |
| SCHEMBL13634241 | 0.74 | LMNA (0.48) | KMT2ALMNACYP2C19ALDH1A1POLB | |
| SCHEMBL30230078 | 0.74 | KMT2A (0.64) | KMT2ATDP1LMNACYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |