Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 2/20 | 0.32 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CCNC | P24863 | 1/20 | 0.32 |
| ▸ | CDK8 | P49336 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28177075 | 0.79 | POLB (0.42) | POLBCYP1A2CYP3A4NPSR1HSD17B10 | |
| SCHEMBL18656646 | 0.72 | ALDH1A1 (0.39) | POLBCYP1A2CYP3A4NPSR1HSD17B10 | |
| SCHEMBL1004648 | 0.67 | POLB (0.55) | POLBNPSR1HSD17B10HPGDALDH1A1 | |
| SCHEMBL16781055 | 0.67 | POLB (0.55) | POLBNPSR1HSD17B10HPGDALDH1A1 | |
| SCHEMBL29812111 | 0.65 | POLB (0.38) | POLBCYP1A2CYP3A4HSD17B10BRD4 | |
| SCHEMBL6699250 | 0.65 | NPC1 (0.43) | POLBCYP1A2CYP3A4NPSR1HPGD | |
| SCHEMBL1003996 | 0.65 | POLB (0.52) | POLBNPSR1HSD17B10HPGDALDH1A1 | |
| Hydrochloric Acid SCHEMBL29030889 | 0.65 | POLB (0.52) | POLBNPSR1HSD17B10HPGDALDH1A1 | |
| SCHEMBL2221293 | 0.65 | POLB (0.52) | POLBNPSR1HSD17B10HPGDALDH1A1 | |
| SCHEMBL17397805 | 0.64 | PDE4D (0.40) | POLBMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |