Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.32 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15777023 | 0.78 | PDE4D (0.57) | PDE4DPOLBCSNK2A2KDRCSNK2B | |
| SCHEMBL1923447 | 0.77 | GAA (0.43) | PDE4DPOLBCSNK2A2KDRCSNK2B | |
| SCHEMBL11201220 | 0.76 | PDE4D (0.46) | PDE4DPOLBCSNK2A2KDRCSNK2B | |
| SCHEMBL9120504 | 0.73 | PDE4D (0.71) | PDE4DPOLBLMNAKMT2A | |
| SCHEMBL30120920 | 0.72 | PDE4D (0.42) | PDE4DPOLBCSNK2A2KDRCSNK2B | |
| SCHEMBL28875154 | 0.71 | PDE4D (0.41) | PDE4DPOLBLMNAL3MBTL1 | |
| Sulfuric Acid SCHEMBL31278552 | 0.71 | GAA (0.39) | PDE4DPOLB | |
| SCHEMBL8597031 | 0.65 | DYRK1A (0.42) | PDE4DCSNK2A2KDRCSNK2BCSNK2A1 | |
| SCHEMBL13638870 | 0.64 | POLB (0.38) | POLBLMNAMEN1KMT2A | |
| SCHEMBL20795351 | 0.64 | CSNK2A2 (0.43) | PDE4DPOLBCSNK2A2KDRCSNK2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3164406-A1 | BORONIC ACID DERIVATIVES AND THERAPEUTIC USES THEREOF | Rempex Pharmaceuticals, Inc. (US) | 2017-05-10 | — | — | EP | disclosed |
| WO-2016003929-A1 | BORONIC ACID DERIVATIVES AND THERAPEUTIC USES THEREOF | REMPEX PHARMACEUTICALS, INC. (US) | 2016-01-07 | — | — | WO | disclosed |