Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 1/20 | 0.36 |
| ▸ | PAICS | P22234 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | CYP2J2 | P51589 | 2/20 | 0.36 |
| ▸ | GPR6 | P46095 | 8/20 | 0.35 |
| ▸ | TYK2 | P29597 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634676 | 0.90 | GPR6 (0.42) | PAICSPIM1CYP2C9EPHX2CYP2J2 | |
| SCHEMBL13634596 | 0.89 | GPR6 (0.38) | PAICSPIM1GPR6CNR1CNR2 | |
| SCHEMBL13634801 | 0.88 | CNR1 (0.46) | PAICSPIM1CYP2C9EPHX2CYP2J2 | |
| SCHEMBL13634512 | 0.86 | SCD (0.39) | PAICSPIM1CYP2C9EPHX2CYP2J2 | |
| SCHEMBL13634831 | 0.86 | PDE10A (0.39) | PAICSCYP2C9EPHX2CYP2J2GPR6 | |
| SCHEMBL13634835 | 0.85 | PIM1 (0.42) | PAICSPIM1CYP2C9GPR6TYK2 | |
| SCHEMBL13634507 | 0.85 | CNR2 (0.43) | PIM1CYP2C9CNR1CNR2CYP2C19 | |
| SCHEMBL13638903 | 0.85 | PDE10A (0.42) | PAICSGPR6CNR1CNR2PDE10A | |
| SCHEMBL13634790 | 0.84 | PIM1 (0.41) | PAICSPIM1GPR6CNR1PDE10A | |
| SCHEMBL13634500 | 0.84 | GPR6 (0.42) | PAICSPIM1CYP2C9EPHX2CYP2J2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |