Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 12/20 | 0.41 |
| ▸ | GPR6 | P46095 | 2/20 | 0.37 |
| ▸ | PAICS | P22234 | 1/20 | 0.37 |
| ▸ | PIM3 | Q86V86 | 5/20 | 0.36 |
| ▸ | PIM2 | Q9P1W9 | 5/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634500 | 0.91 | GPR6 (0.42) | PIM1GPR6PAICSCNR1PDE10A | |
| SCHEMBL13638762 | 0.90 | PDE10A (0.40) | PIM1GPR6PAICSCNR1PDE10A | |
| SCHEMBL13634793 | 0.88 | SCD (0.40) | GPR6PAICSCNR1 | |
| SCHEMBL13634596 | 0.86 | GPR6 (0.38) | PIM1GPR6PAICSCNR1 | |
| SCHEMBL13634676 | 0.85 | GPR6 (0.42) | PIM1GPR6PAICSCNR1PDE10A | |
| SCHEMBL13634675 | 0.84 | PDE10A (0.48) | CNR1PDE10A | |
| SCHEMBL13638871 | 0.84 | TGFBR1 (0.36) | PIM1GPR6PAICSCNR1PDE10A | |
| SCHEMBL13634506 | 0.84 | PIM1 (0.39) | PIM1PIM3PIM2CNR1 | |
| SCHEMBL13634671 | 0.83 | PDE10A (0.46) | PIM1GPR6PAICSPIM3PIM2 | |
| SCHEMBL13634792 | 0.83 | PDE10A (0.46) | PIM1GPR6PAICSPIM3PIM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |