Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 2/20 | 0.36 |
| ▸ | SCD5 | Q86SK9 | 2/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | TNK1 | Q13470 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | PIN1 | Q13526 | 3/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NAPEPLD | Q6IQ20 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15888681 | 0.95 | SCD (0.33) | SCDSCD5HRH3PARP1TNK1 | |
| SCHEMBL13634903 | 0.95 | SCD (0.36) | SCDSCD5HRH3PARP1TNK1 | |
| SCHEMBL13638891 | 0.88 | IRAK4 (0.38) | SCDSCD5KMT2AIRAK4OPRK1 | |
| SCHEMBL2770055 | 0.88 | PARP1 (0.38) | SCDSCD5PARP1TNK1KMT2A | |
| SCHEMBL13638996 | 0.87 | SCD (0.35) | SCDSCD5KMT2AIRAK4OPRK1 | |
| SCHEMBL13639001 | 0.87 | KMT2A (0.38) | SCDSCD5KMT2AOPRK1 | |
| SCHEMBL2770243 | 0.87 | KMT2A (0.38) | SCDSCD5KMT2AOPRK1 | |
| SCHEMBL13638916 | 0.87 | HDAC8 (0.43) | SCDSCD5PIN1 | |
| SCHEMBL13638912 | 0.87 | KMT2A (0.47) | KMT2AIRAK4OPRK1 | |
| SCHEMBL13638774 | 0.87 | SCD (0.38) | SCDSCD5HRH3PIN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |