Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 2/20 | 0.38 |
| ▸ | SCD5 | Q86SK9 | 2/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 3/20 | 0.34 |
| ▸ | NAPEPLD | Q6IQ20 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 4/20 | 0.33 |
| ▸ | PIM3 | Q86V86 | 4/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 4/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634906 | 0.94 | SCD (0.38) | SCDSCD5PIN1NAPEPLDPIM1 | |
| SCHEMBL13638951 | 0.90 | PDCD1 (0.40) | SCDSCD5PIN1HPGDPDCD1 | |
| SCHEMBL13639003 | 0.90 | PIN1 (0.37) | SCDSCD5PIN1NAPEPLDPIM1 | |
| SCHEMBL13162738 | 0.90 | NAPEPLD (0.35) | SCDSCD5PIN1NAPEPLDCHEK1 | |
| SCHEMBL13270441 | 0.90 | NAPEPLD (0.35) | SCDSCD5PIN1NAPEPLDCHEK1 | |
| SCHEMBL13164119 | 0.90 | NAPEPLD (0.35) | SCDSCD5PIN1NAPEPLDCHEK1 | |
| SCHEMBL2770055 | 0.89 | PARP1 (0.38) | SCDSCD5PIN1 | |
| SCHEMBL2770606 | 0.89 | PIN1 (0.37) | SCDSCD5PIN1NAPEPLDPIM1 | |
| SCHEMBL2770504 | 0.89 | PIN1 (0.37) | SCDSCD5PIN1NAPEPLDPIM1 | |
| SCHEMBL13638916 | 0.89 | HDAC8 (0.43) | SCDSCD5PIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |