SCHEMBL13638916 — predicted protein targets

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	HDAC8	Q9BY41	2/20	0.43

▸	HDAC6	Q9UBN7	2/20	0.43

▸	HDAC1	Q13547	1/20	0.43

▸	S1PR1	P21453	1/20	0.43

▸	SCD	O00767	2/20	0.35

▸	SCD5	Q86SK9	2/20	0.35

▸	ACKR3	P25106	1/20	0.35

▸	DRD2	P14416	2/20	0.34

▸	SIGMAR1	Q99720	2/20	0.34

▸	PIN1	Q13526	3/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL13634729	0.95	S1PR1 (0.45)	HDAC8HDAC6HDAC1S1PR1SCD
SCHEMBL13634557	0.94	S1PR1 (0.42)	HDAC8HDAC6HDAC1S1PR1SCD
SCHEMBL13638996	0.91	SCD (0.35)	S1PR1SCDSCD5
SCHEMBL13638948	0.90	SCD (0.34)	HDAC8HDAC6HDAC1S1PR1SCD
SCHEMBL13638777	0.90	GRM2 (0.35)	HDAC8HDAC6HDAC1S1PR1SCD
SCHEMBL2770055	0.89	PARP1 (0.38)	SCDSCD5ACKR3PIN1
SCHEMBL13638774	0.89	SCD (0.38)	SCDSCD5PIN1
SCHEMBL13638951	0.89	PDCD1 (0.40)	SCDSCD5ACKR3PIN1
SCHEMBL13639003	0.88	PIN1 (0.37)	SCDSCD5PIN1
SCHEMBL2770504	0.88	PIN1 (0.37)	SCDSCD5PIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-8304547-B2	Azolecarboxamide compound or salt thereof	ASTELLAS PHARMA INC. (JP)	2012-11-06	—	—	US	disclosed