Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR6 | P46095 | 5/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
| ▸ | SCD | O00767 | 1/20 | 0.34 |
| ▸ | GLS | O94925 | 3/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13638817 | 0.93 | CYP2C9 (0.35) | GPR6KMT2AOPRK1FGFR1SCD | |
| SCHEMBL13634599 | 0.92 | GPR6 (0.37) | GPR6KMT2AOPRK1SCDGLS | |
| SCHEMBL13638926 | 0.90 | GPR6 (0.37) | GPR6KMT2AOPRK1SCDMEN1 | |
| SCHEMBL13634684 | 0.88 | MCHR1 (0.39) | FGFR1F10IRAK4 | |
| SCHEMBL13638989 | 0.88 | MCHR1 (0.35) | GPR6KMT2AOPRK1SCDMEN1 | |
| SCHEMBL13638883 | 0.88 | MCHR1 (0.35) | GPR6KMT2AOPRK1FGFR1SCD | |
| SCHEMBL13638933 | 0.88 | MCHR1 (0.39) | KMT2AGLSF10 | |
| SCHEMBL13638765 | 0.87 | MCHR1 (0.37) | GPR6KMT2AOPRK1SCDMEN1 | |
| SCHEMBL13638938 | 0.87 | MCHR1 (0.37) | GPR6KMT2AOPRK1SCDMEN1 | |
| SCHEMBL13638826 | 0.87 | MCHR1 (0.40) | KMT2AOPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |