Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | GPR6 | P46095 | 5/20 | 0.35 |
| ▸ | SCD | O00767 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | TNK1 | Q13470 | 1/20 | 0.34 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13638883 | 0.94 | MCHR1 (0.35) | MCHR1KMT2AOPRK1GPR6SCD | |
| SCHEMBL13634583 | 0.94 | GLS (0.39) | MCHR1KMT2AOPRK1GPR6SCD | |
| SCHEMBL13634599 | 0.92 | GPR6 (0.37) | KMT2AOPRK1GPR6SCDHRH3 | |
| SCHEMBL13638911 | 0.91 | KMT2A (0.36) | MCHR1KMT2AOPRK1GPR6SCD | |
| SCHEMBL13638939 | 0.91 | KMT2A (0.36) | MCHR1KMT2AOPRK1GPR6SCD | |
| SCHEMBL13638933 | 0.91 | MCHR1 (0.39) | MCHR1KMT2APARP1TNK1ACKR3 | |
| SCHEMBL13638926 | 0.91 | GPR6 (0.37) | KMT2AOPRK1GPR6SCDMEN1 | |
| SCHEMBL13634719 | 0.91 | HRH3 (0.39) | MCHR1KMT2AOPRK1GPR6SCD | |
| SCHEMBL13638938 | 0.90 | MCHR1 (0.37) | MCHR1KMT2AOPRK1GPR6SCD | |
| SCHEMBL13638765 | 0.90 | MCHR1 (0.37) | MCHR1KMT2AOPRK1GPR6SCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |