Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 5/20 | 0.78 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 4/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | IDE | P14735 | 1/20 | 0.54 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | NPY1R | P25929 | 1/20 | 0.53 |
| ▸ | NPY2R | P49146 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3436898 | 0.92 | IRAK4 (0.78) | IRAK4HPGDCHEK1LMNAMAPT | |
| SCHEMBL13818336 | 0.85 | MAPT (0.60) | IRAK4HPGDCHEK1LMNAMAPT | |
| SCHEMBL13638811 | 0.84 | RAB9A (0.63) | IRAK4HPGDCHEK1LMNAMAPT | |
| SCHEMBL13162020 | 0.83 | IRAK4 (0.59) | IRAK4HPGDCHEK1LMNAMAPT | |
| SCHEMBL13634538 | 0.82 | CHEK1 (0.59) | IRAK4HPGDCHEK1LMNAMAPT | |
| SCHEMBL2138509 | 0.82 | CHEK1 (0.59) | IRAK4HPGDCHEK1LMNAMAPT | |
| SCHEMBL6628193 | 0.81 | TDP1 (0.86) | IRAK4HPGDLMNAMAPTMEN1 | |
| SCHEMBL2139170 | 0.79 | IRAK4 (0.61) | IRAK4HPGDCHEK1LMNAMAPT | |
| SCHEMBL10851498 | 0.78 | HPGD (1.00) | HPGDLMNAMAPTNPC1RAB9A | |
| SCHEMBL12790094 | 0.77 | IRAK4 (0.77) | IRAK4HPGDCHEK1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |