Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.63 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.61 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13638902 | 0.84 | IRAK4 (0.78) | RAB9AIRAK4CHEK1HDAC1HDAC6 | |
| SCHEMBL3436898 | 0.83 | IRAK4 (0.78) | RAB9AIRAK4SMN1; SMN2CHEK1KDM4E | |
| SCHEMBL2771222 | 0.83 | RAB9A (0.60) | RAB9AIRAK4SMN1; SMN2CHEK1KDM4E | |
| SCHEMBL13634536 | 0.83 | RAB9A (0.60) | RAB9AIRAK4SMN1; SMN2CHEK1KDM4E | |
| SCHEMBL18600237 | 0.81 | RAB9A (0.55) | RAB9AIRAK4SMN1; SMN2CHEK1KDM4E | |
| SCHEMBL14207028 | 0.80 | CHEK1 (0.59) | RAB9AIRAK4SMN1; SMN2CHEK1KDM4E | |
| SCHEMBL352098 | 0.80 | KDM4E (0.68) | RAB9ASMN1; SMN2CHEK1KDM4EHDAC3 | |
| SCHEMBL14207144 | 0.79 | CHEK1 (0.83) | RAB9ASMN1; SMN2CHEK1MAPTTSHR | |
| SCHEMBL14207142 | 0.78 | CHEK1 (0.81) | RAB9ASMN1; SMN2CHEK1MAPTTSHR | |
| SCHEMBL14207146 | 0.78 | CHEK1 (0.81) | RAB9ASMN1; SMN2CHEK1MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |