Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 10/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.38 |
| ▸ | GPR6 | P46095 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | RBP4 | P02753 | 1/20 | 0.35 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13638995 | 0.93 | SCD (0.43) | SCDCYP2C9EPHX2CYP2J2SCN9A | |
| SCHEMBL13634619 | 0.92 | SCN9A (0.43) | SCDSCN9ASCN5AGPR6HPGD | |
| SCHEMBL13638935 | 0.90 | SCD (0.44) | SCDCYP2C9EPHX2CYP2J2SCN9A | |
| SCHEMBL2772305 | 0.90 | SCD (0.45) | SCDCYP2C9EPHX2CYP2J2SCN9A | |
| SCHEMBL13270708 | 0.87 | SCD (0.43) | SCDCYP2C9EPHX2CYP2J2SCN9A | |
| SCHEMBL13638941 | 0.86 | MAP3K7 (0.43) | SCDCYP2C9EPHX2CYP2J2GPR6 | |
| SCHEMBL13634703 | 0.85 | PDE4D (0.42) | SCDGPR6HPGD | |
| SCHEMBL13634606 | 0.82 | IRAK4 (0.43) | SCDGPR6HPGDLMNA | |
| SCHEMBL13634679 | 0.82 | IRAK4 (0.43) | SCDGPR6HPGDLMNA | |
| SCHEMBL13634621 | 0.80 | GPR6 (0.39) | SCDGPR6HDAC3HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |