Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 7/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 7/20 | 0.44 |
| ▸ | KDM1A | O60341 | 2/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 5/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13162268 | 1.00 | EPHX1 (0.47) | EPHX1EPHX2KDM1APDK2MCHR1 | |
| Hydrochloric Acid SCHEMBL2772564 | 0.98 | EPHX1 (0.46) | EPHX1EPHX2KDM1APDK2MCHR1 | |
| SCHEMBL25587585 | 0.84 | ALDH1A1 (0.44) | EPHX1EPHX2KDM1APDK2MCHR1 | |
| SCHEMBL18701737 | 0.84 | ALDH1A1 (0.44) | EPHX1EPHX2KDM1APDK2MCHR1 | |
| SCHEMBL10223183 | 0.84 | ALDH1A1 (0.44) | EPHX1EPHX2KDM1APDK2MCHR1 | |
| SCHEMBL6419218 | 0.83 | EPHX1 (0.45) | EPHX1EPHX2KDM1AMCHR1ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL28024964 | 0.83 | MCHR1 (0.49) | EPHX1KDM1APDK2MCHR1HRH4 | |
| SCHEMBL4634407 | 0.81 | EPHX1 (0.49) | EPHX1EPHX2KDM1AALDH1A1CYP2C19 | |
| SCHEMBL2807431 | 0.81 | EPHX1 (0.49) | EPHX1EPHX2KDM1AALDH1A1CYP2C19 | |
| SCHEMBL2807429 | 0.81 | EPHX1 (0.49) | EPHX1EPHX2KDM1AALDH1A1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |