Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 5/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 8/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KDM5A | P29375 | 3/20 | 0.36 |
| ▸ | TEAD1 | P28347 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26139073 | 0.85 | ALDH1A1 (0.45) | EPHX1EPHX2CYP2D6MCHR1ALDH1A1 | |
| SCHEMBL26140553 | 0.85 | ALDH1A1 (0.45) | EPHX1EPHX2CYP2D6MCHR1ALDH1A1 | |
| SCHEMBL13162268 | 0.83 | EPHX1 (0.47) | EPHX1EPHX2KDM1AMCHR1ALDH1A1 | |
| SCHEMBL13638962 | 0.83 | EPHX1 (0.47) | EPHX1EPHX2KDM1AMCHR1ALDH1A1 | |
| SCHEMBL6419317 | 0.83 | EPHX1 (0.45) | EPHX1EPHX2KDM1AKDM5ATEAD1 | |
| SCHEMBL4635146 | 0.83 | EPHX1 (0.45) | EPHX1EPHX2KDM1AKDM5ATEAD1 | |
| Hydrochloric Acid SCHEMBL2772564 | 0.81 | EPHX1 (0.46) | EPHX1EPHX2KDM1ACYP2D6MCHR1 | |
| SCHEMBL24767079 | 0.79 | EPHX2 (0.51) | EPHX1EPHX2CYP2D6MCHR1ALDH1A1 | |
| SCHEMBL16906841 | 0.79 | EPHX2 (0.51) | EPHX1EPHX2CYP2D6MCHR1ALDH1A1 | |
| SCHEMBL27161625 | 0.79 | CYP2D6 (0.40) | EPHX1EPHX2CYP2D6MCHR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050014789-A1 | Amide derivatives as selective serotonin re-uptake inhibitors | PFIZER INC | 2005-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014789-A1 | Amide derivatives as selective serotonin re-uptake inhibitors | SLC6A4, HTR3C, HTR3A | EPHX1 1834/4885EPHX2 1291/4885KDM1A 3725/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.