Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 3/20 | 0.37 |
| ▸ | SCD | O00767 | 2/20 | 0.36 |
| ▸ | SCD5 | Q86SK9 | 2/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | NAPEPLD | Q6IQ20 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 2/20 | 0.34 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.34 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13163170 | 0.94 | PIN1 (0.36) | PIN1SCDSCD5CHEK1HRH3 | |
| SCHEMBL2770606 | 0.94 | PIN1 (0.37) | PIN1SCDSCD5CHEK1HRH3 | |
| SCHEMBL2770504 | 0.94 | PIN1 (0.37) | PIN1SCDSCD5CHEK1HRH3 | |
| SCHEMBL2773453 | 0.94 | PIN1 (0.35) | PIN1SCDSCD5CHEK1HRH3 | |
| SCHEMBL2771174 | 0.93 | PIN1 (0.37) | PIN1SCDSCD5CHEK1HRH3 | |
| SCHEMBL13163169 | 0.93 | PIN1 (0.35) | PIN1SCDSCD5CHEK1HRH3 | |
| SCHEMBL2770287 | 0.93 | PIN1 (0.36) | PIN1SCDSCD5CHEK1HRH3 | |
| SCHEMBL15888680 | 0.93 | PIN1 (0.36) | PIN1SCDSCD5CHEK1HRH3 | |
| SCHEMBL13270405 | 0.93 | PIN1 (0.36) | PIN1SCDSCD5HRH3NAPEPLD | |
| SCHEMBL2774531 | 0.93 | NAPEPLD (0.37) | PIN1SCDSCD5CHEK1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |