Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634922 | 0.90 | HDAC3 (0.43) | HPGDHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL13270408 | 0.88 | ACHE (0.42) | HPGDHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL13270465 | 0.86 | KMT2A (0.44) | HPGDPKMGAAHTTL3MBTL1 | |
| SCHEMBL13270448 | 0.84 | KMT2A (0.56) | GAAALDH1A1KDM4EL3MBTL1SMN1; SMN2 | |
| SCHEMBL13634769 | 0.82 | HDAC3 (0.41) | HPGDHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL13162967 | 0.80 | HDAC8 (0.50) | HDAC1HDAC8HDAC6 | |
| SCHEMBL13634813 | 0.80 | KMT2A (0.41) | HPGDGAAALDH1A1HTTL3MBTL1 | |
| SCHEMBL2770606 | 0.79 | PIN1 (0.37) | HPGDHTTPIM1MEN1MAPK1 | |
| SCHEMBL13162968 | 0.78 | HPGD (0.38) | HPGDHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL13163171 | 0.75 | F10 (0.36) | HPGDTP53PKMGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |