Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 6/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 3/20 | 0.32 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | FDPS | P14324 | 1/20 | 0.30 |
| ▸ | PTGIR | P43119 | 1/20 | 0.30 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12298894 | 1.00 | CA2 (0.33) | CA2MAPK1CA1PTGER2ALDH1A1 | |
| SCHEMBL11981966 | 0.87 | — | — | |
| SCHEMBL13639140 | 0.87 | — | — | |
| SCHEMBL15178057 | 0.86 | PTGER2 (0.36) | CA2MAPK1CA1PTGER2ALDH1A1 | |
| SCHEMBL13849974 | 0.86 | PTGER2 (0.36) | CA2MAPK1CA1PTGER2ALDH1A1 | |
| SCHEMBL11981982 | 0.83 | — | — | |
| SCHEMBL11981889 | 0.81 | — | — | |
| SCHEMBL2444823 | 0.81 | UGT2B7 (0.31) | — | |
| SCHEMBL13639137 | 0.78 | TSHR (0.31) | — | |
| SCHEMBL11981878 | 0.78 | LMNA (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1481976-B1 | 8-AZAPROSTAGLANDIN DERIVATIVE COMPOUNDS AND DRUGS CONTAINING THE COMPOUNDS AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO (JP) | 2012-11-07 | — | — | EP | disclosed |