Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | PLA2G4B | P0C869 | 8/20 | 0.56 |
| ▸ | RARB | P10826 | 4/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | THRA | P10827 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14569973 | 0.81 | TSHR (0.62) | TP53TSHRPLA2G4BRARBPKM | |
| SCHEMBL1981044 | 0.80 | PKM (0.62) | TP53TSHRPLA2G4BPKMHTT | |
| SCHEMBL21499295 | 0.79 | ESR1 (0.72) | TP53 | |
| SCHEMBL4511317 | 0.79 | DRD2 (0.64) | TP53TSHRPLA2G4BRARBPKM | |
| Hydrochloric Acid SCHEMBL5070229 | 0.79 | PKM (0.61) | TP53TSHRPLA2G4BPKMHTT | |
| SCHEMBL736876 | 0.78 | TP53 (0.89) | TP53TSHRPLA2G4BRARBPKM | |
| SCHEMBL10798086 | 0.78 | TP53 (0.89) | TP53TSHRPLA2G4BRARBPKM | |
| SCHEMBL175191 | 0.78 | TP53 (0.77) | TP53TSHRPLA2G4BRARBPKM | |
| SCHEMBL250102 | 0.77 | EBP (0.69) | TP53TSHRPLA2G4BPKMHTT | |
| Hydrochloric Acid SCHEMBL21225052 | 0.77 | PKM (0.59) | TP53TSHRPLA2G4BPKMHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1481976-B1 | 8-AZAPROSTAGLANDIN DERIVATIVE COMPOUNDS AND DRUGS CONTAINING THE COMPOUNDS AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO (JP) | 2012-11-07 | — | — | EP | disclosed |